The regulation of gene transcription is not simply dependent on the presence or absence of
DNA-binding transcription factors that turn genes on or off, but also involves processes …

DNA methyltransferase is needed for normal development, perhaps because DNA
methylation plays a part in the control of gene activity. It is clear that the methylation of …

DNA methylation: A molecular lock Page 1 Dispatch R305 DNA methylation: A molecular lock
Zahava Siegfried and Howard Cedar In mammals, the promoters of expressed genes are …

Despite thousands of articles about 5-methylcytosine (m5C) residues in vertebrate DNA,
there is still controversy concerning the role of genomic m5C in normal vertebrate …

Methylation of the cytosine base in DNA, DNA methylation, is an essential epigenetic mark
in mammals that contributes to the regulation of transcription. Several advances have been …

Recent technological advances have made it possible to decode DNA methylomes at single-
base-pair resolution under various physiological conditions. Many aberrant or differentially …

Over three decades ago DNA methylation had been suggested to play a role in the
regulation of gene expression. This chapter reviews the development of this field of research …

DNA methylation is a significant regulator of gene expression, and its role in carcinogenesis
recently has been a subject of remarkable interest. The aim of this review is to analyze the …

DNA methylation is commonly associated with gene silencing, and a link between histone
deacetylation and DNA methylation has been established. However, the transcriptional …

The field of epigenetics has recently moved to the forefront of studies relating to diverse
processes such as transcriptional regulation, chromatin structure, genome integrity, and …