Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease
MW Manning, LA Cassis, J Huang… - Vascular …, 2002 - journals.sagepub.com
Abdominal aortic aneurysms (AAA) have a high prevalence in aged populations and are
responsible for a large number of deaths. Despite the widespread nature of the disease …
responsible for a large number of deaths. Despite the widespread nature of the disease …
The pathophysiologic basis of abdominal aortic aneurysm progression: a critical appraisal
JHN Lindeman - Expert review of cardiovascular therapy, 2015 - Taylor & Francis
An aneurysm of the abdominal aorta is a common pathology and a major cause of sudden
death in the elderly. Currently, abdominal aortic aneurysms (AAAs) can only be treated by …
death in the elderly. Currently, abdominal aortic aneurysms (AAAs) can only be treated by …
Mechanisms of abdominal aortic aneurysm formation
A Daugherty, LA Cassis - Current atherosclerosis reports, 2002 - Springer
Abdominal aortic aneurysms (AAA) are permanent dilations in the infra-renal area in which
the arterial tissue is characterized by inflammation and medial degeneration. AAAs are a …
the arterial tissue is characterized by inflammation and medial degeneration. AAAs are a …
Inflammation in abdominal aortic aneurysms: cellular infiltrate and cytokine profiles
MJ Eagleton - Vascular, 2012 - journals.sagepub.com
Abdominal aortic aneurysm (AAA) pathogenesis occurs as a result of the altered
homeostasis of the aortic vessel wall structural proteins. This results in weakening, and …
homeostasis of the aortic vessel wall structural proteins. This results in weakening, and …
Mouse models of abdominal aortic aneurysms
A Daugherty, LA Cassis - Arteriosclerosis, thrombosis, and …, 2004 - Am Heart Assoc
Many mouse models of abdominal aortic aneurysms have been developed that use a
diverse array of methods for producing the disease, including genetic manipulation and …
diverse array of methods for producing the disease, including genetic manipulation and …
Twenty years of studying AngII (angiotensin II)-induced abdominal aortic pathologies in mice: continuing questions and challenges to provide insight into the human …
AngII (angiotensin II) infusion in mice has been used to provide mechanistic insight into
human abdominal aortic aneurysms for over 2 decades. This is a technically facile animal …
human abdominal aortic aneurysms for over 2 decades. This is a technically facile animal …
[HTML][HTML] Development of pharmacotherapies for abdominal aortic aneurysms
The cardiovascular field is still searching for a treatment for abdominal aortic aneurysms
(AAA). This inflammatory disease often goes undiagnosed until a late stage and associated …
(AAA). This inflammatory disease often goes undiagnosed until a late stage and associated …
Translational relevance and recent advances of animal models of abdominal aortic aneurysm
J Sénémaud, G Caligiuri, H Etienne… - … , and vascular biology, 2017 - Am Heart Assoc
Human abdominal aortic aneurysm (AAA) pathophysiology is not yet completely understood.
In conductance arteries, the insoluble extracellular matrix, synthesized by vascular smooth …
In conductance arteries, the insoluble extracellular matrix, synthesized by vascular smooth …
Abdominal aortic aneurysms: an autoimmune disease?
VP Jagadesham, DJA Scott, SR Carding - Trends in molecular medicine, 2008 - cell.com
Abdominal aortic aneurysms (AAAs) are a multifactorial degenerative vascular disorder. One
of the defining features of the pathophysiology of aneurysmal disease is inflammation …
of the defining features of the pathophysiology of aneurysmal disease is inflammation …
Abdominal aortic aneurysm: novel mechanisms and therapies
FM Davis, DL Rateri, A Daugherty - Current opinion in cardiology, 2015 - journals.lww.com
Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion in
Cardiology Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion …
Cardiology Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion …