Dectin-2 is a C-type lectin receptor that recognizes high mannose polysaccharides.
Cryptococcus neoformans, a yeast-form fungal pathogen, is rich in polysaccharides in its cell …

The cell walls and capsules of Cryptococcus neoformans, a yeast-type fungal pathogen, are
rich in polysaccharides. Dectin-2 is a C-type lectin receptor (CLR) that recognizes high …

C-type lectin receptors (CLRs) are diverse, trans-membrane proteins that function as pattern
recognition receptors (PRRs) which are necessary for orchestrating immune responses …

Dectin‐1 is known as a sole receptor for β‐glucan, a major cell wall component of fungal
microorganisms. In the current study, we examined the role of this molecule in the host …

Objectives and design Hypersensitivity pneumonitis (HP) is a pulmonary disease caused by
repeated exposure to various aspiration antigens, including bacteria and fungi. Although …

Cryptococcus neoformans is rich in polysaccharides of the cell wall and capsule. Dectin‐2
recognizes high‐mannose polysaccharides and plays a central role in the immune response …

We assessed the role of Dectin-1 in the immune response to the pathogenic fungus
Coccidioides, both in vitro and in vivo, using mice with a targeted mutation in Clec7a …

Background Streptococcus pneumoniae, a major causative bacterial pathogen of community-
acquired pneumonia, possesses a thick polysaccharide capsule. Host defense against this …

Phagocytosis by innate immune cells is an important process for protection against multiple
pathologies and is particularly important for resistance to infection. However, phagocytosis …

Dectin-1 is an innate antifungal C-type lectin receptor necessary for protective antifungal
immunity. We recently discovered that Dectin-1 is involved in controlling fungal infections of …