Hemorrhagic stroke which consists of subarachnoid hemorrhage and intracerebral
hemorrhage is a dominant cause of death and disability worldwide. Although great efforts …

Stroke is a devastating disease associated with high mortality and disability worldwide, and
is generally classified as ischemic or hemorrhagic, which share certain similar …

Cerebral ischemia-reperfusion (CIR) injury is initiated by the generation of reactive oxygen
species (ROS), which leads to the oxidation of cellular proteins, DNA, and lipids as an initial …

Subarachnoid hemorrhage (SAH) is a common cerebrovascular disease with high mortality
and disability rates. Despite progressive advances in drugs and surgical techniques …

Cerebral ischemia-reperfusion (I/R) injury is the predominant causes for the poor prognosis
of ischemic stroke patients after reperfusion therapy. Currently, potent therapeutic …

Stroke is one of the most devastating neurological disabilities and brain's vulnerability
towards it proves to be fatal and socio‐economic loss of millions of people worldwide …

Melatonin has many protective effects against ischemic stroke, but the underlying
neuroprotective mechanisms are not fully understood. Our aim was to explore the …

Stroke represents one of the most common causes of brain's vulnerability for many millions
of people worldwide. The plethora of physiopathological events associated with brain …

Melatonin (n-acetyl-5-methoxy-tryptamine), a naturally occurring indole produced mainly by
the pineal gland, is a well known antioxidant. Stroke (cerebral ischemia) is the second …

Because of its favorable action profile in humans, melatonin is a particularly interesting
candidate as a neuroprotectant in acute ischemic stroke. Until now, the signaling …