Eukaryotic DNA methyltransferases–structure and function
RLP Adams - Bioessays, 1995 - Wiley Online Library
Methylation of DNA plays an important role in the control of gene expression in higher
eukaryotes. This is largely achieved by the packaging of methylated DNA into chromatin …
eukaryotes. This is largely achieved by the packaging of methylated DNA into chromatin …
DNA demethylation
T Roldán-Arjona, RR Ariza - In: DNA and RNA Modification …, 2009 - books.google.com
Eukaryotic DNA methylation is performed by DNA-methyltransferases that catalyze transfer
of a methyl group from S-adenosyl-L-methionine to carbon 5 of cytosine bases in DNA …
of a methyl group from S-adenosyl-L-methionine to carbon 5 of cytosine bases in DNA …
Molecular processes connecting DNA methylation patterns with DNA methyltransferases and histone modifications in mammalian genomes
A Jeltsch, J Broche, P Bashtrykov - Genes, 2018 - mdpi.com
DNA methylation is an essential part of the epigenome chromatin modification network,
which also comprises several covalent histone protein post-translational modifications. All …
which also comprises several covalent histone protein post-translational modifications. All …
Dynamics of DNA methylation pattern
CL Hsieh - Current opinion in genetics & development, 2000 - Elsevier
Methylation patterns are the result of de novo methylation, demethylation, and the
maintenance of existing methylation. Although the existence and identity of an active …
maintenance of existing methylation. Although the existence and identity of an active …
[PDF][PDF] The role of mammalian DNA methyltransferases in the regulation of gene expression
J Turek-Plewa, PP Jagodzinski - Cellular and Molecular Biology Letters, 2005 - Citeseer
The term epigenetic modification denotes reversible traits of gene expression that do not
include alterations to the DNA sequence. These epigenetic alterations are responsible for …
include alterations to the DNA sequence. These epigenetic alterations are responsible for …
DNA methyltransferases
TH Bestor, GL Verdine - Current opinion in cell biology, 1994 - Elsevier
Mammals have long been known to tag their DNA by the addition of methyl groups to
cytosine residues. Only quite recently, however, has the functional significance of DNA …
cytosine residues. Only quite recently, however, has the functional significance of DNA …
DNA methylation and the regulation of gene transcription
JT Attwood, RL Yung, BC Richardson - Cellular and Molecular Life …, 2002 - Springer
The regulation of gene transcription is not simply dependent on the presence or absence of
DNA-binding transcription factors that turn genes on or off, but also involves processes …
DNA-binding transcription factors that turn genes on or off, but also involves processes …
DNA methylation, methyltransferases, and cancer
KD Robertson - Oncogene, 2001 - nature.com
The field of epigenetics has recently moved to the forefront of studies relating to diverse
processes such as transcriptional regulation, chromatin structure, genome integrity, and …
processes such as transcriptional regulation, chromatin structure, genome integrity, and …
Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA
Proper DNA methylation patterns are essential for mammalian development and
differentiation. DNA methyltransferases (DNMTs) primarily establish and maintain global …
differentiation. DNA methyltransferases (DNMTs) primarily establish and maintain global …