Genetic imprinting during impaired spermatogenesis

S Hartmann, M Bergmann, RM Bohle… - MHR: Basic science …, 2006 - academic.oup.com
Disorders in genetic imprinting are discussed as potential genetic risk in assisted
reproduction technology (ART), where most of the natural selection mechanisms are …

[HTML][HTML] Poor semen parameters are associated with abnormal methylation of imprinted genes in sperm DNA

B Song, Y Chen, C Wang, G Li, Z Wei, X He… - Reproductive Biology …, 2022 - Springer
Background Altered sperm DNA methylation patterns of imprinted genes as well as certain
spermatogenesis-related genes has been proposed as a possible mechanism of male …

Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients

H Kobayashi, A Sato, E Otsu, H Hiura… - Human molecular …, 2007 - academic.oup.com
Recent studies suggest that assisted reproductive technologies (ART), which involve the
isolation, handling and culture of gametes and early embryos, are associated with an …

[HTML][HTML] Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility

SS Hammoud, J Purwar, C Pflueger, BR Cairns… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To evaluate the associations between proper protamine incorporation and
DNA methylation at imprinted loci. DESIGN: Experimental research study. SETTING …

Epigenetic germline mosaicism in infertile men

S Laurentino, J Beygo, V Nordhoff… - Human molecular …, 2015 - academic.oup.com
Imprinted genes are expressed either from the paternal or the maternal allele, because the
other allele has been silenced in the mother's or father's germline. Imprints are characterized …

[HTML][HTML] Aberrant DNA methylation at imprinted genes in testicular sperm retrieved from men with obstructive azoospermia and undergoing vasectomy reversal

A Minor, V Chow, S Ma - Reproduction, 2011 - rep.bioscientifica.com
Male factor infertility has been associated with abnormal DNA methylation at imprinted
genes. Little information is available on the status of imprinting in the sperm of men with …

Semen samples showing an increased rate of spermatozoa with imprinting errors have a negligible effect in the outcome of assisted reproduction techniques

C Camprubí, M Pladevall, M Grossmann, N Garrido… - Epigenetics, 2012 - Taylor & Francis
The topic of imprinting defects present in the sperm of infertile patients has been addressed
by several reports in the last few years. However, whether methylation abnormalities at one …

Abnormal methylation of imprinted genes in human sperm is associated with oligozoospermia

CJ Marques, P Costa, B Vaz, F Carvalho… - MHR-Basic Science …, 2008 - academic.oup.com
Genomic imprinting marks in the male germ line are already established in the adult
germinal stem cell population. We studied the methylation patterns of H19 and MEST …

Impairment of sperm DNA methylation in male infertility: a meta‐analytic study

D Santi, S De Vincentis, E Magnani, G Spaggiari - Andrology, 2017 - Wiley Online Library
Considering the widespread use of assisted reproductive techniques (ART), DNA
methylation of specific genes involved in spermatogenesis achieves increasingly clinical …

Sperm DNA integrity status is associated with DNA methylation signatures of imprinted genes and non-imprinted genes

B Song, C Wang, Y Chen, G Li, Y Gao, F Zhu… - Journal of Assisted …, 2021 - Springer
Purpose To evaluate the association between the DNA methylation of specific genes and
sperm DNA integrity status in human sperm samples. Methods A total of 166 semen samples …