A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis
DNA methylation is an indispensible epigenetic modification required for regulating the
expression of mammalian genomes. Immunoprecipitation-based methods for DNA …
expression of mammalian genomes. Immunoprecipitation-based methods for DNA …
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
DNA methylation plays key roles in diverse biological processes such as X chromosome
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …
MEDME: an experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment
M Pelizzola, Y Koga, AE Urban… - Genome …, 2008 - genome.cshlp.org
DNA methylation is an important component of epigenetic modifications that influences the
transcriptional machinery and is aberrant in many human diseases. Several methods have …
transcriptional machinery and is aberrant in many human diseases. Several methods have …
Meffil: efficient normalization and analysis of very large DNA methylation datasets
Motivation DNA methylation datasets are growing ever larger both in sample size and
genome coverage. Novel computational solutions are required to efficiently handle these …
genome coverage. Novel computational solutions are required to efficiently handle these …
Evaluation of affinity-based genome-wide DNA methylation data: effects of CpG density, amplification bias, and copy number variation
DNA methylation is an essential epigenetic modification that plays a key role associated with
the regulation of gene expression during differentiation, but in disease states such as …
the regulation of gene expression during differentiation, but in disease states such as …
Profiling genome-wide DNA methylation
DNA methylation is an epigenetic modification that plays an important role in regulating
gene expression and therefore a broad range of biological processes and diseases. DNA …
gene expression and therefore a broad range of biological processes and diseases. DNA …
Quantitative comparison of genome-wide DNA methylation mapping technologies
DNA methylation plays a key role in regulating eukaryotic gene expression. Although
mitotically heritable and stable over time, patterns of DNA methylation frequently change in …
mitotically heritable and stable over time, patterns of DNA methylation frequently change in …
Methylated DNA immunoprecipitation (medip)
F Mohn, M Weber, D Schübeler, TC Roloff - DNA methylation: methods …, 2009 - Springer
Methylated DNA immunoprecipitation (MeDIP) is a versatile immunocapturing approach for
unbiased detection of methylated DNA. In brief, genomic DNA is randomly sheared by …
unbiased detection of methylated DNA. In brief, genomic DNA is randomly sheared by …
Methyl-DNA immunoprecipitation (MeDIP): hunting down the DNA methylome
FV Jacinto, E Ballestar, M Esteller - Biotechniques, 2008 - Future Science
One of the most challenging projects in the field of epigenetics is the generation of detailed
functional maps of DNA methylation in different cell and tissue types in normal and disease …
functional maps of DNA methylation in different cell and tissue types in normal and disease …
DMRfinder: efficiently identifying differentially methylated regions from MethylC-seq data
JM Gaspar, RP Hart - BMC bioinformatics, 2017 - Springer
Background DNA methylation is an epigenetic modification that is studied at a single-base
resolution with bisulfite treatment followed by high-throughput sequencing. After alignment …
resolution with bisulfite treatment followed by high-throughput sequencing. After alignment …