Background Hypothyroidism is associated with obesity, and thyroid hormones are involved
in the regulation of body composition, including fat mass. Genome-wide association studies …

Thyroid hormones play key roles in cellular growth, development and metabolism. Although
there is a strong genetic influence on thyroid hormone levels, the genes involved are widely …

Background Thyroid hormones have important roles in growth, development and control of
metabolism, and their dysregulation can lead to disease. Objectives To identify genes …

To date only a fraction of the genetic footprint of thyroid function has been clarified. We
report a genome-wide association study meta-analysis of thyroid function in up to 271,040 …

Thyroid hormone is essential for normal metabolism and development, and overt
abnormalities in thyroid function lead to common endocrine disorders affecting …

Purpose Thyroid hormones are essential for the normal function of almost all human tissues,
and have critical roles in metabolism, differentiation and growth. Free triiodothyronine (fT3) …

Objectives Previous studies have shown interindividual variation in free thyroxine (FT4)
serum levels and thyroid stimulating hormone (TSH) in healthy persons. Genetic factors …

Background: Elevations or deficits in thyroid hormone levels are responsible for a wide
range of neonatal and adult phenotypes. Several genome-wide, candidate gene, and meta …

Thyroid stimulating hormone (TSH) hormone levels are normally tightly regulated within an
individual; thus, relatively small variations may indicate thyroid disease. Genome-wide …

Thyroid hormones (THs) are key regulators of cellular growth, development, and
metabolism. The thyroid gland secretes two THs, thyroxine (T4) and triiodothyronine (T3) …