Genetic associations with neonatal thyroid-stimulating hormone levels

FY Alul, OA Shchelochkov, SL Berberich, JC Murray… - Pediatric …, 2013 - nature.com
Background: Elevations or deficits in thyroid hormone levels are responsible for a wide
range of neonatal and adult phenotypes. Several genome-wide, candidate gene, and meta …

Genetic determinants of thyroid function in children

TA Mulder, PJ Campbell, PN Taylor… - European journal of …, 2023 - academic.oup.com
Objective Genome-wide association studies in adults have identified 42 loci associated with
thyroid stimulating hormone (TSH) and 21 loci associated with free thyroxine (FT4) …

Maternal and birth characteristics are determinants of offspring thyroid function

TIM Korevaar, L Chaker, VWV Jaddoe… - The Journal of …, 2016 - academic.oup.com
Background: Intrauterine adaptation to the outside environment is an important mechanism
via which the fetus increases its chance to thrive after birth. Therefore, various maternal …

A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents

TRH Nielsen, EVR Appel, M Svendstrup, JD Ohrt… - PLoS …, 2017 - journals.plos.org
Background Hypothyroidism is associated with obesity, and thyroid hormones are involved
in the regulation of body composition, including fat mass. Genome-wide association studies …

TSH concentrations in parents and their offspring: a cross-sectional family-based analysis

C Girschik, SC Drogge, B Kowall… - European Journal of …, 2021 - academic.oup.com
Objective Studies that evaluated the genetic influences on thyroid-stimulating hormone
(TSH) concentrations were primarily performed in twin cohorts. The aim of this study was to …

Genetic analysis in children with transient thyroid dysfunction or subclinical hypothyroidism detected on neonatal screening

M Satoh, K Aso, S Ogikubo, A Ogasawara… - Clinical Pediatric …, 2009 - jstage.jst.go.jp
About 30% of children with elevated TSH levels during neonatal screening have a transient
form of disorder. On the other hand, it has been reported that subclinical hypothyroidism …

Divergent patterns of thyrotropin and other thyroidal parameters in relationship with the sex of healthy neonates and infants less than two years old: a longitudinal …

I Legakis, D Adamopoulos, I Stamatiou, A Gryparis… - Thyroid, 2019 - liebertpub.com
Background: A longitudinal study was conducted in full-term healthy infants who were born
between 2015 and 2017 in Athens, Greece, to elucidate the evolution of thyrotropin (TSH) …

Lack of association between thyrotropin receptor gene polymorphisms and subclinical hypothyroidism in children

F Teofoli, M Camilot, L Tatò - Journal of endocrinological investigation, 2007 - Springer
Subclinical hypothyroidism is defined as a serum TSH level above the statistically set
reference range, associated to normal free thyroid hormone concentrations. Genetic and …

[HTML][HTML] Perinatal factors associated with neonatal thyroid-stimulating hormone in normal newborns

SY Lee - Annals of pediatric endocrinology & metabolism, 2016 - ncbi.nlm.nih.gov
Purpose This study was to evaluate the effect of neonatal, maternal, and delivery factors on
neonatal thyroid-stimulating hormone (TSH) of healthy newborns. Methods Medical records …

TSH levels in relation to gestation, birth weight and sex

M Korada, MS Pearce, E Avis, S Turner… - Hormone …, 2009 - karger.com
Aims: Low birth weight is associated with hypothyroidism and an adverse metabolic profile
in later life. Our aim was to examine the relationship between neonatal TSH and birth …