[HTML][HTML] Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies
The human oxytocin (OXT) system is implicated in the regulation of complex social
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …
Oxytocin receptor gene methylation as a molecular marker for severity of depressive symptoms in affective disorder patients
B Ludwig, L Carlberg, K Kienesberger, P Swoboda… - BMC psychiatry, 2022 - Springer
Background Oxytocin (OXT) is a neuropeptide and hormone involved in emotional
functioning and also seems to play a role in moderating the stress response. Both preclinical …
functioning and also seems to play a role in moderating the stress response. Both preclinical …
Dynamic DNA methylation changes in the maternal oxytocin gene locus (OXT) during pregnancy predict postpartum maternal intrusiveness
Maternal behavior (MB) is observable across mammals and represents an important feature
of environmental variation during early postnatal development. Oxytocin (OT) plays a crucial …
of environmental variation during early postnatal development. Oxytocin (OT) plays a crucial …
Methylation of the oxytocin receptor gene in clinically depressed patients compared to controls: The role of OXTR rs53576 genotype
I Reiner, MH Van IJzendoorn… - Journal of psychiatric …, 2015 - Elsevier
The emerging field of epigenetics provides a biological basis for gene-environment
interactions relevant to depression. We focus on DNA methylation of exon 1 and 2 of the …
interactions relevant to depression. We focus on DNA methylation of exon 1 and 2 of the …
DNA methylation of the oxytocin receptor across neurodevelopmental disorders
MT Siu, SJ Goodman, I Yellan, DT Butcher… - Journal of autism and …, 2021 - Springer
Many neurodevelopmental disorders (NDDs) share common learning and behavioural
impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we …
impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we …
Epigenetic regulation of the oxytocin receptor gene: implications for behavioral neuroscience
Genetic approaches have improved our understanding of the neurobiological basis of social
behavior and cognition. For instance, common polymorphisms of genes involved in oxytocin …
behavior and cognition. For instance, common polymorphisms of genes involved in oxytocin …
Epigenetic modification of the oxytocin receptor gene: implications for autism symptom severity and brain functional connectivity
E Andari, S Nishitani, G Kaundinya… - …, 2020 - nature.com
The role of oxytocin in social cognition has attracted tremendous interest in social
neuroscience and psychiatry. Some studies have reported improvement in social symptoms …
neuroscience and psychiatry. Some studies have reported improvement in social symptoms …
Natural variation in maternal care and cross-tissue patterns of oxytocin receptor gene methylation in rats
This article is part of a Special Issue “Parental Care”. Since the first report of maternal care
effects on DNA methylation in rats, epigenetic modifications of the genome in response to …
effects on DNA methylation in rats, epigenetic modifications of the genome in response to …
Oxytocin receptor exon III methylation in the umbilical cord blood of newborns with prenatal exposure to crack cocaine
T Baptista, LA de Azeredo, A Zaparte… - Frontiers in Cell and …, 2021 - frontiersin.org
Background Prenatal cocaine exposure (PCE) is associated with behavioral, cognitive, and
social consequences in children that might persist into later development. However, there …
social consequences in children that might persist into later development. However, there …
DNA methylation of OXTR is associated with parasympathetic nervous system activity and amygdala morphology
K Lancaster, L Goldbeck, MH Puglia… - Social cognitive and …, 2018 - academic.oup.com
Oxytocin has anxiolytic properties whose mechanisms of action are still being identified.
DNA methylation in the promoter region of the oxytocin receptor gene (OXTR), an epigenetic …
DNA methylation in the promoter region of the oxytocin receptor gene (OXTR), an epigenetic …