Genetic and epigenetic signatures associated with plasma oxytocin levels in children and adolescents with autism spectrum disorder
SK Siecinski, SN Giamberardino, M Spanos… - Autism …, 2023 - Wiley Online Library
Abstract Oxytocin (OT), the brain's most abundant neuropeptide, plays an important role in
social salience and motivation. Clinical trials of the efficacy of OT in autism spectrum …
social salience and motivation. Clinical trials of the efficacy of OT in autism spectrum …
Oxytocin receptor gene polymorphism (rs2254298) interacts with familial risk for psychopathology to predict symptoms of depression and anxiety in adolescent girls
The nonapeptide oxytocin and its receptor have been implicated in the regulation of
mammalian social behavior and stress physiology. Evidence is accumulating that the quality …
mammalian social behavior and stress physiology. Evidence is accumulating that the quality …
Oxytocin receptor expression patterns in the human brain across development
Oxytocin plays a vital role in social behavior and homeostatic processes, with animal models
indicating that oxytocin receptor (OXTR) expression patterns in the brain influence behavior …
indicating that oxytocin receptor (OXTR) expression patterns in the brain influence behavior …
Oxytocin receptor gene DNA methylation: a biomarker of treatment response in obsessive-compulsive disorder?
MA Schiele, C Thiel, L Kollert, L Fürst… - Psychotherapy and …, 2020 - karger.com
Introduction: Obsessive-compulsive disorder (OCD) is associated with high chronicity and
treatment resistance, indicating the need for early therapy response markers enabling fast …
treatment resistance, indicating the need for early therapy response markers enabling fast …
The altered promoter methylation of oxytocin receptor gene in autism
M Elagoz Yuksel, B Yuceturk, OF Karatas… - Journal of …, 2016 - Taylor & Francis
Autism spectrum disorder (ASD) is one of the lifelong existing disorders. Abnormal
methylation status of gene promoters of oxytonergic system has been implicated as among …
methylation status of gene promoters of oxytonergic system has been implicated as among …
Oxytocin pathway genes: evolutionary ancient system impacting on human affiliation, sociality, and psychopathology
Oxytocin (OT), a nonapeptide signaling molecule originating from an ancestral peptide,
appears in different variants across all vertebrate and several invertebrate species …
appears in different variants across all vertebrate and several invertebrate species …
Neuroimaging genetics of oxytocin: A transcriptomics-informed systematic review
The last couple of decades have witnessed a rapid accumulation of studies implicating
oxytocin (OT) in several neurobiological underpinnings of human behaviour and their …
oxytocin (OT) in several neurobiological underpinnings of human behaviour and their …
Methylation of OXT and OXTR genes, central oxytocin, and social behavior in female macaques
Oxytocin (OXT) and its receptor (OXTR) are encoded by OXT and OXTR, respectively.
Variable methylation of these genes has been linked to variability in sociability and …
Variable methylation of these genes has been linked to variability in sociability and …
Association between the oxytocin receptor (OXTR) gene and children's social cognition at 18 months
M Wade, TJ Hoffmann, K Wigg… - Genes, Brain and …, 2014 - Wiley Online Library
At 18 months, children engage in a variety of social behaviors that reflect their nascent ability
to understand the intentions of other people (eg joint attention, empathy, cooperation and …
to understand the intentions of other people (eg joint attention, empathy, cooperation and …
Oxytocin receptors (OXTR) and early parental care: An interaction that modulates psychiatric disorders
Oxytocin plays an important role in the modulation of social behavior in both typical and
atypical contexts. Also, the quality of early parental care sets the foundation for long-term …
atypical contexts. Also, the quality of early parental care sets the foundation for long-term …