The Methylation of Clock Genes in Perinatal Depression: Which Role for Oxytocin?
S Iodice, M Di Paolo, JL Barkin, L Tarantini… - Frontiers in …, 2021 - frontiersin.org
Background: Perinatal Depression (PD) is a widespread disabling condition that is
hypothesized to be associated with abnormalities in circadian rhythms and neuropeptide …
hypothesized to be associated with abnormalities in circadian rhythms and neuropeptide …
A role of oxytocin receptor gene brain tissue expression quantitative trait locus rs237895 in the intergenerational transmission of the effects of maternal childhood …
Objective Women exposed to childhood maltreatment (CM) are more likely to exhibit
insensitive parenting, which may have consequences for their offspring's development …
insensitive parenting, which may have consequences for their offspring's development …
A multi-modal MRI analysis of brain structure and function in relation to OXT methylation in maltreated children and adolescents
S Nishitani, TX Fujisawa, D Hiraoka, K Makita… - Translational …, 2021 - nature.com
Child maltreatment dysregulates the brain's oxytocinergic system, resulting in dysfunctional
attachment patterns. However, how the oxytocinergic system in children who are maltreated …
attachment patterns. However, how the oxytocinergic system in children who are maltreated …
Epigenetic dynamics in infancy and the impact of maternal engagement
KM Krol, RG Moulder, TS Lillard, T Grossmann… - Science …, 2019 - science.org
The contribution of nature versus nurture to the development of human behavior has been
debated for centuries. Here, we offer a piece to this complex puzzle by identifying the human …
debated for centuries. Here, we offer a piece to this complex puzzle by identifying the human …
Variation in the oxytocin receptor gene is associated with increased risk for anxiety, stress and depression in individuals with a history of exposure to early life stress
Background Oxytocin is a neuropeptide that is involved in the regulation of mood, anxiety
and social biology. Genetic variation in the oxytocin receptor gene (OXTR) has been …
and social biology. Genetic variation in the oxytocin receptor gene (OXTR) has been …
Maternal oxytocin treatment at birth increases epigenetic age in male offspring
Exogenous oxytocin is widely used to induce or augment labor with little understanding of
the impact on offspring development. In rodent models, including the prairie vole (Microtus …
the impact on offspring development. In rodent models, including the prairie vole (Microtus …
The association of childhood maltreatment with depression and anxiety is not moderated by the oxytocin receptor gene
MS Tollenaar, ML Molendijk, BWJH Penninx… - European archives of …, 2017 - Springer
Background The oxytocin receptor (OXTR) gene may be involved in resilience or
vulnerability towards stress, and hence in the development of stress-related disorders. There …
vulnerability towards stress, and hence in the development of stress-related disorders. There …
Epigenetic modification of the oxytocin receptor gene influences the perception of anger and fear in the human brain
In humans, the neuropeptide oxytocin plays a critical role in social and emotional behavior.
The actions of this molecule are dependent on a protein that acts as its receptor, which is …
The actions of this molecule are dependent on a protein that acts as its receptor, which is …
Genetic imaging of the association of oxytocin receptor gene (OXTR) polymorphisms with positive maternal parenting
Background: Well-validated models of maternal behavior in small-brain mammals posit a
central role of oxytocin in parenting, by reducing stress and enhancing the reward value of …
central role of oxytocin in parenting, by reducing stress and enhancing the reward value of …
DNA methylation at the neonatal state and at the time of diagnosis: preliminary support for an association with the estrogen receptor 1, gamma-aminobutyric acid B …
JB Nissen, CS Hansen, A Starnawska… - Frontiers in …, 2016 - frontiersin.org
Obsessive–compulsive disorder (OCD) is a neuropsychiatric disorder. Non-genetic factors
and their interaction with genes have attracted increasing attention. Epigenetics is regarded …
and their interaction with genes have attracted increasing attention. Epigenetics is regarded …