DNA methylation and gene expression
H Cedar - DNA methylation: biochemistry and biological …, 1984 - Springer
Understanding the mechanisms involved in the regulation of gene expression in eukaryotic
organisms is one of the major challenges facing the modern molecular biologist. Despite …
organisms is one of the major challenges facing the modern molecular biologist. Despite …
DNA methylation, chromatin structure and the regulation of gene expression
M Graessmann, A Graessmann - DNA methylation: molecular biology and …, 1993 - Springer
It is still not clear how eukaryotic cells regulate gene expression during differentiation and in
the differentiated state. There is increasing experimental evidence that this requires a wide …
the differentiated state. There is increasing experimental evidence that this requires a wide …
[图书][B] DNA methylation: molecular biology and biological significance
J Jost, H Saluz - 2013 - books.google.com
The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see
first chapter). Recognition of its possible physiologi cal role in eucaryotes was first …
first chapter). Recognition of its possible physiologi cal role in eucaryotes was first …
DNA methylation in eukaryotic cells
A Razin, H Cedar - International review of cytology, 1984 - Elsevier
Publisher Summary This chapter discusses DNA methylation in eukaryotic cells. DNA
methylation pattern undergoes discrete changes, especially during the process of …
methylation pattern undergoes discrete changes, especially during the process of …
Effects of DNA methylation on DNA-binding proteins and gene expression
PH Tate, AP Bird - Current opinion in genetics & development, 1993 - Elsevier
DNA methyltransferase is needed for normal development, perhaps because DNA
methylation plays a part in the control of gene activity. It is clear that the methylation of …
methylation plays a part in the control of gene activity. It is clear that the methylation of …
Gene methylation patterns and expression
J Yisraeli, M Szyf - DNA methylation: biochemistry and biological …, 1984 - Springer
Three basic approaches have been employed in the study of the effect of DNA methylation
of particular genes on their expression. One approach uses chemicals that cause …
of particular genes on their expression. One approach uses chemicals that cause …
Hypomethylation of DNA in the regulation of gene expression
LA Chandler, PA Jones - The Molecular Biology of Cell Determination and …, 1988 - Springer
Cellular differentiation involves the activation of a specific set of genes as well as the
suppression of those genes associated with the differentiation of other cell types …
suppression of those genes associated with the differentiation of other cell types …
Eukaryotic DNA methylation and gene expression
A Weissbach, C Ward, A Bolden - Current topics in cellular regulation, 1989 - Elsevier
Publisher Summary This chapter discusses eukaryotic DNA methylation and gene
expression. The methylation of DNA in animal cells is a postreplicative process involving the …
expression. The methylation of DNA in animal cells is a postreplicative process involving the …
DNA methylation and gene activity.
H Cedar - Cell, 1988 - europepmc.org
The above experiments support a relatively simple model to explain the role of DNA
methylation in vivo. Most tissue-specific genes are methylated. The methyl groups may …
methylation in vivo. Most tissue-specific genes are methylated. The methyl groups may …
[图书][B] DNA methylation: development, genetic disease and cancer
W Doerfler, P Böhm - 2006 - books.google.com
It has become apparent that the genomes of many organisms are characterized by unique
patterns of DNA methylation which can differ from genome segment to genome segment and …
patterns of DNA methylation which can differ from genome segment to genome segment and …