Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic
Reference strains are a key component of laboratory research, providing a common
background allowing for comparisons across a community of researchers. However …
background allowing for comparisons across a community of researchers. However …
Lineages derived from Cryptococcus neoformans type strain H99 support a link between the capacity to be pleomorphic and virulence
The pathogenic yeast Cryptococcus neoformans causes nearly 200,000 deaths annually in
immunocompromised individuals. Cryptococcus cells can undergo substantial …
immunocompromised individuals. Cryptococcus cells can undergo substantial …
The interplay of phenotype and genotype in Cryptococcus neoformans disease
S Altamirano, KM Jackson, K Nielsen - Bioscience Reports, 2020 - portlandpress.com
Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …
Importance of Clinical Isolates in Cryptococcus neoformans Research
KM Jackson, M Ding, K Nielsen - Journal of Fungi, 2023 - mdpi.com
The human pathogenic fungus Cryptococcus neoformans is a global health concern.
Previous research in the field has focused on studies using reference strains to identify …
Previous research in the field has focused on studies using reference strains to identify …
Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii
The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …
infections in immunocompromised as well as immunocompetent individuals. Although …
Microevolution of a Standard Strain ofCryptococcus neoformans Resulting in Differences in Virulence and Other Phenotypes
SP Franzot, J Mukherjee, R Cherniak… - Infection and …, 1998 - Am Soc Microbiol
Cryptococcus neoformans is a major fungal pathogen for patients with debilitated immune
systems. However, no information is available on the stability of virulence or of phenotypes …
systems. However, no information is available on the stability of virulence or of phenotypes …
Beyond the big three: systematic analysis of virulence factors in Cryptococcus neoformans
J Kronstad, WH Jung, G Hu - Cell Host & Microbe, 2008 - cell.com
The fungal pathogen Cryptococcus neoformans has three major virulence factors: growth at
37° C, capsule synthesis, and melanin formation. Recently in Cell, Liu et al.(2008) employed …
37° C, capsule synthesis, and melanin formation. Recently in Cell, Liu et al.(2008) employed …
Profiling a killer, the development of Cryptococcus neoformans
L Kozubowski, J Heitman - FEMS microbiology reviews, 2012 - academic.oup.com
The ability of fungi to transition between unicellular and multicellular growth has a profound
impact on our health and the economy. Many important fungal pathogens of humans …
impact on our health and the economy. Many important fungal pathogens of humans …
Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence
KL Ormerod, CA Morrow, EWL Chow… - G3: Genes …, 2013 - academic.oup.com
The opportunistic fungal pathogen Cryptococcus neoformans is a leading cause of mortality
among the human immunodeficiency virus/acquired immunodeficiency syndrome …
among the human immunodeficiency virus/acquired immunodeficiency syndrome …
[PDF][PDF] Microevolution of serial clinical isolates of Cryptococcus neoformans var. grubii and C. gattii. mBio 8: e00166-17
Y Chen, RA Farrer, C Giamberardino, S Sakthikumar… - 2017 - dukespace.lib.duke.edu
The pathogenic species of Cryptococcus are a major cause of mortality owing to severe
infections in immunocompromised as well as immunocompetent individuals. Although …
infections in immunocompromised as well as immunocompetent individuals. Although …