A pathology atlas of the human cancer transcriptome
INTRODUCTION Cancer is a leading cause of death worldwide, and there is great need to
define the molecular mechanisms driving the development and progression of individual …
define the molecular mechanisms driving the development and progression of individual …
A pan-cancer proteomic perspective on The Cancer Genome Atlas
Protein levels and function are poorly predicted by genomic and transcriptomic analysis of
patient tumours. Therefore, direct study of the functional proteome has the potential to …
patient tumours. Therefore, direct study of the functional proteome has the potential to …
[HTML][HTML] Exploring cancer genomic data from the cancer genome atlas project
JS Lee - BMB reports, 2016 - ncbi.nlm.nih.gov
Abstract The Cancer Genome Atlas (TCGA) has compiled genomic, epigenomic, and
proteomic data from more than 10,000 samples derived from 33 types of cancer, aiming to …
proteomic data from more than 10,000 samples derived from 33 types of cancer, aiming to …
Proteogenomic data and resources for pan-cancer analysis
Summary The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium
(CPTAC) investigates tumors from a proteogenomic perspective, creating rich multi-omics …
(CPTAC) investigates tumors from a proteogenomic perspective, creating rich multi-omics …
[HTML][HTML] Perspective on oncogenic processes at the end of the beginning of cancer genomics
L Ding, MH Bailey, E Porta-Pardo, V Thorsson… - Cell, 2018 - cell.com
Summary The Cancer Genome Atlas (TCGA) has catalyzed systematic characterization of
diverse genomic alterations underlying human cancers. At this historic junction marking the …
diverse genomic alterations underlying human cancers. At this historic junction marking the …
Connecting genomic alterations to cancer biology with proteomics: the NCI Clinical Proteomic Tumor Analysis Consortium
The National Cancer Institute (NCI) Clinical Proteomic Tumor Analysis Consortium is
applying the latest generation of proteomic technologies to genomically annotated tumors …
applying the latest generation of proteomic technologies to genomically annotated tumors …
Pan-cancer molecular classes transcending tumor lineage across 32 cancer types, multiple data platforms, and over 10,000 cases
F Chen, Y Zhang, DL Gibbons, B Deneen… - Clinical Cancer …, 2018 - AACR
Abstract Purpose: The Cancer Genome Atlas data resources represent an opportunity to
explore commonalities across cancer types involving multiple molecular levels, but tumor …
explore commonalities across cancer types involving multiple molecular levels, but tumor …
The Cancer Genome Atlas Clinical Explorer: a web and mobile interface for identifying clinical–genomic driver associations
HJ Lee, J Palm, SM Grimes, HP Ji - Genome medicine, 2015 - Springer
Abstract Background The Cancer Genome Atlas (TCGA) project has generated genomic
data sets covering over 20 malignancies. These data provide valuable insights into the …
data sets covering over 20 malignancies. These data provide valuable insights into the …
Systematic transcriptional analysis of human cell lines for gene expression landscape and tumor representation
Cell lines are valuable resources as model for human biology and translational medicine. It
is thus important to explore the concordance between the expression in various cell lines vis …
is thus important to explore the concordance between the expression in various cell lines vis …
Assessing the clinical utility of cancer genomic and proteomic data across tumor types
Molecular profiling of tumors promises to advance the clinical management of cancer, but
the benefits of integrating molecular data with traditional clinical variables have not been …
the benefits of integrating molecular data with traditional clinical variables have not been …