Large-scale mutant screens in zebrafish have led to the identification of more than 50 genes
affecting various aspects of neural development and function, including neural induction …

The central nervous system (CNS) is the most complex tissue of vertebrates. Recently, the
zebrafish has emerged as a powerful genetic system for studying early development, and …

In recent years, the zebrafish has become a popular system for studying vertebrate
development. Large scale mutant searches have led to the identification of> 400 genes with …

This special issue of Developmental Neurobiology contains sixteen papers that will give
readers a taste of some of the areas of neuroscience in which research using zebrafish is …

The accessibility and simplicity of the zebrafish embryo have led to fruitful examinations of
how vertebrate embryos develop, at the cellular level. Recently, several groups have …

In a large scale mutagenesis screen for embryonic mutants in zebrafish, we have identified
63 mutations in 24 loci affecting the morphogenesis of the zebrafish brain. The expression of …

Zebrafish provide a rapid and effective means for assessing gene function in the vertebrate
nervous system. By employing gain-and loss-of-function techniques it is possible to obtain …

The early zebrafish embryo develops a simple primary nervous system that controls motility.
Similar to that of the nematode C. elegans, this primary nervous system is composed of a …

During development of the zebrafish forebrain, a simple scaffold of axon pathways is
pioneered by a small number of neurons. We show that boundaries of expression domains …

How does the nervous system develop? This problem has intrigued embryologists for more
than a century. In fact, early investigators formulated many of the fundamental questions …