The traditional view that gene and environment interactions control disease susceptibility
can now be expanded to include epigenetic reprogramming as a key determinant of origins …

Epigenetics has the potential to explain various biological phenomena that have heretofore
defied complete explication. This review describes the various types of endogenous human …

The ways in which epigenetic modifications fix the effects of early environmental events,
ensuring sustained responses to transient stimuli that result in modified gene expression …

Although genetics determines endocrine phenotypes, it cannot fully explain the great
variability and reversibility of the system in response to environmental changes. Evidence …

Plasticity in developmental programming has evolved in order to provide the best chances of
survival and reproductive success to the organism under changing environments …

The epigenome undergoes significant remodeling during tissue and organ development,
which coincides with a period of exquisite sensitivity to environmental exposures. In the case …

Background: Epigenetic mechanisms provide one potential explanation for how
environmental influences in early life cause long-term changes in chronic disease …

Epigenetics is rising to prominence in biology as a mechanism by which environmental
factors have intermediate-term effects on gene expression without changing the underlying …

Environmental factors during early life are critical for the later metabolic health of the
individual and of future progeny. In our obesogenic environment, it is of great socioeconomic …

The ways in which epigenetic modifications fix the effects of early environmental events,
ensuring sustained responses to transient stimuli, which result in modified gene expression …