Results Eighty-two patients (90%) exhibited microscopic hematuria; 51 (62%), exhibited only
microscopic hematuria, whereas the remaining 31 additionally had proteinuria (38%); 28 …

Complement factor H related protein 5 (CFHR5) nephropathy is a monogenic disorder of
complement regulation that is endemic in Cyprus. The disease is characterised by …

Complement component 3 glomerulopathy (C3G) is a recently defined entity comprising of
dense deposit disease and C3 glomerulonephritis. The key histological feature is the …

C3 and Bf alleles were examined in the general population, in 67 patients with biopsy-
confirmed mesangial IgA nephropathy and 81 patients with other types of …

There have been few new therapies for patients with chronic kidney disease in the last
decade. However, the management of patients affected by genetic kidney disease is rapidly …

The most frequent cause of familial glomerular hematuria is thin basement membrane
nephropathy (TBMN) caused by germline COL4A3 or COL4A4 gene mutations. Less …

This study examined how often children with persistent familial hematuria were from families
where hematuria segregated with the known genetic locus for the condition known as …

Introduction: Membranoproliferative glomerulonephritis type II or dense deposit disease
(MPGN II/DDD) causes chronic renal dysfunction that progresses to end stage renal disease …

Abstract Collagen IV nephropathies (COL4Ns) comprise benign familial microscopic
hematuria, thin basement membrane nephropathy (TBMN), X-linked Alport syndrome (AS) …

Genetic and acquired abnormalities in complement factor H (CFH) have been associated
with two different human renal diseases: haemolytic uraemic syndrome and membrano …