Notes on the role of dynamic DNA methylation in mammalian development
TH Bestor, JR Edwards… - Proceedings of the …, 2015 - National Acad Sciences
It has been nearly 40 y since it was suggested that genomic methylation patterns could be
transmitted via maintenance methylation during S phase and might play a role in the …
transmitted via maintenance methylation during S phase and might play a role in the …
DNA methylation and embryogenesis
A Razin, H Cedar - DNA methylation: molecular biology and biological …, 1993 - Springer
A large number of studies have documented the methylation patterns of individual genes
and repeated sequences in different tissues of various mammalian species. This has …
and repeated sequences in different tissues of various mammalian species. This has …
[引用][C] The essentials of DNA methylation
A Bird - cell, 1992 - Elsevier
An obstacle to progress in understanding eukaryotic DNA methylation has been the lack of a
good genetic systemthe most favorable eukaryotes for genetic analysis (yeasts …
good genetic systemthe most favorable eukaryotes for genetic analysis (yeasts …
Dynamics of DNA methylation during development
M Brandeis, M Ariel, H Cedar - Bioessays, 1993 - Wiley Online Library
DNA methylation plays a role in the repression of gene expression in animal cells. In the
mouse preimplantation embryo, most genes are unmethylated but a wave of de novo …
mouse preimplantation embryo, most genes are unmethylated but a wave of de novo …
Genomic patterns of DNA methylation: targets and function of an epigenetic mark
M Weber, D Schübeler - Current opinion in cell biology, 2007 - Elsevier
Methylation of cytosines can mediate epigenetic gene silencing and is the only known DNA
modification in eukaryotes. Recent efforts to map DNA methylation across mammalian …
modification in eukaryotes. Recent efforts to map DNA methylation across mammalian …
[HTML][HTML] Formation of methylation patterns in the mammalian genome
MS Turker, TH Bestor - Mutation Research/Reviews in Mutation Research, 1997 - Elsevier
Cytosine methylation in mammals is an epigenetic modification required for viability of the
developing embryo. It has been suggested that DNA methylation plays important roles in X …
developing embryo. It has been suggested that DNA methylation plays important roles in X …
Transposon silencing and imprint establishment in mammalian germ cells
TH Bestor, D Bourc'his - Cold Spring Harbor symposia on …, 2004 - symposium.cshlp.org
The first mammalian DNA methyltransferase to be identified was cloned by chromatographic
purification of the protein to homogeneity, determination of the sequence of cyanogen …
purification of the protein to homogeneity, determination of the sequence of cyanogen …
Cytosine methylation and mammalian development
Programmed methylation and demethylation of regulatory sequences has been proposed to
play a central role in vertebrate development. We report here that the methylation status of …
play a central role in vertebrate development. We report here that the methylation status of …
Targets and dynamics of promoter DNA methylation during early mouse development
J Borgel, S Guibert, Y Li, H Chiba, D Schübeler… - Nature …, 2010 - nature.com
DNA methylation is extensively reprogrammed during the early phases of mammalian
development, yet genomic targets of this process are largely unknown. We optimized …
development, yet genomic targets of this process are largely unknown. We optimized …
Expression of various genes is controlled by DNA methylation during mammalian development
M Ehrlich - Journal of cellular biochemistry, 2003 - Wiley Online Library
Despite thousands of articles about 5-methylcytosine (m5C) residues in vertebrate DNA,
there is still controversy concerning the role of genomic m5C in normal vertebrate …
there is still controversy concerning the role of genomic m5C in normal vertebrate …
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