Epigenetics has the potential to explain various biological phenomena that have heretofore
defied complete explication. This review describes the various types of endogenous human …

Epigenetic marks change during fetal development, adult life, and aging. Some changes
play an important role in the establishment and regulation of gene programs, but others …

The phenotype of an individual is the result of complex interactions between genotype,
epigenome and current, past and ancestral environment, leading to lifelong remodelling of …

While the eukaryotic genome is the same throughout all somatic cells in an organism, there
are specific structures and functions that discern one type of cell from another. These …

Improved understanding of the multilayer regulation of the human genome has led to a
greater appreciation of environmental, nutritional, and epigenetic risk factors for human …

Epigenetic control of gene expression programs is essential for normal organismal
development and cellular function. Abrogation of epigenetic regulation is seen in many …

This review considers the emerging relationships between environmental factors and
epigenetic alterations and the application of genome-wide assessments to better define …

Several lines of evidence point to the early origin of adult onset disease. A key question is:
what are the mechanisms that mediate the effects of the early environment on our health …

The ways in which epigenetic modifications fix the effects of early environmental events,
ensuring sustained responses to transient stimuli that result in modified gene expression …

Epigenetics is a rapidly growing field of biology that studies the changes in gene expression
that are not due to alterations in the DNA sequence but rather the chemical modifications of …