DNA methylation is a prevalent epigenetic modification in vertebrates, and it has been
shown to be involved the regulation of gene expression and embryo development. However …

Post-fertilization epigenome reprogramming erases epigenetic marks transmitted through
gametes and establishes new marks during mid-blastula stages. The mouse embryo …

Methylation of cytosines in the CG context (mCG) is the most abundant DNA modification in
vertebrates that plays crucial roles in cellular differentiation and identity. After fertilization …

DNA methylation reprogramming, the erasure of DNA methylation patterns shortly after
fertilization and their reestablishment during subsequent early development, is essential for …

DNA methylation is an epigenetic mark associated with transcriptional repression and
essential for proper vertebrate development. Because of its association with human …

methylcytosine is a major epigenetic modification that is sometimes called" the fifth
nucleotide." However, our knowledge of how offspring inherit the DNA methylome from …

Two waves of DNA methylation reprogramming occur during mammalian embryogenesis;
during preimplantation development and during primordial germ cell (PGC) formation …

DNA methylation is a major epigenetic modification that undergoes dramatic changes in two
epigenetic reprogramming windows during development: first in preimplantation embryos …

Early vertebrate embryos must achieve totipotency and prepare for zygotic genome
activation (ZGA). To understand this process, we determined the DNA methylation (DNAme) …

DNA methylation is dynamic through the life of an organism. Previous studies have primarily
focused on DNA methylation changes during very early embryogenesis. In this study, global …