A comparison of genome-wide DNA methylation patterns between different vascular tissues from patients with coronary heart disease

MS Nazarenko, AV Markov, IN Lebedev, MB Freidin… - PLoS …, 2015 - journals.plos.org
Epigenetic mechanisms of gene regulation in context of cardiovascular diseases are of
considerable interest. So far, our current knowledge of the DNA methylation profiles for …

DNA methylation map of human atherosclerosis

S Zaina, H Heyn, FJ Carmona, N Varol… - Circulation …, 2014 - Am Heart Assoc
Background—Epigenetic alterations may contribute to the development of atherosclerosis.
In particular, DNA methylation, a reversible and highly regulated DNA modification, could …

Genome-wide DNA methylation patterns in coronary heart disease

X Wang, AH Liu, ZW Jia, K Pu, KY Chen, H Guo - Herz, 2018 - search.proquest.com
Background To better understand the molecular mechanisms of atherosclerosis, we
conducted a comparative analysis of DNA methylation patterns in right coronary arteries in …

[HTML][HTML] Integrated DNA methylation and gene expression analysis in the pathogenesis of coronary artery disease

L Miao, RX Yin, QH Zhang, XJ Hu, F Huang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
To evaluate DNA methylation sites and gene expression associated with coronary artery
disease (CAD) and the possible pathological mechanism involved, we performed (1) …

Identification of hypo-and hypermethylated genes related to atherosclerosis by a genome-wide analysis of DNA methylation

Y Yamada, T Nishida, H Horibe… - International …, 2014 - spandidos-publications.com
Epigenetic modification, particularly changes in DNA methylation at gene promoters, is
implicated in the pathogenesis of atherosclerosis. However, the analysis of DNA methylation …

Genome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients

P Sharma, G Garg, A Kumar, F Mohammad, SR Kumar… - Gene, 2014 - Elsevier
Background The alteration in the epigenome forms an interface between the genotype and
the environment. Epigenetic alteration is expected to make a significant contribution to the …

An update on the cell-free DNA-derived methylome as a non-invasive biomarker for coronary artery disease

M Dash, B Mahajan, GM Dar, P Sahu… - The International Journal …, 2024 - Elsevier
Cardiovascular diseases are the foremost contributor to global mortality, presenting a
complex etiology and an expanding array of risk factors. Coronary artery disease …

Aberrant DNA methylation in the pathogenesis of atherosclerosis

Z Hai, W Zuo - Clinica Chimica Acta, 2016 - Elsevier
Atherosclerosis, a multifactorial disease of large-and intermediate-sized arteries, is
characterized by the accumulation of lipids and the proliferation of arterial smooth muscle …

Global DNA methylation analysis of human atherosclerotic plaques reveals extensive genomic hypomethylation and reactivation at imprinted locus 14q32 involving …

E Aavik, H Lumivuori, O Leppänen, T Wirth… - European heart …, 2015 - academic.oup.com
Aims We conducted a genome-wide analysis to identify differentially methylated genes in
atherosclerotic lesions. Methods DNA methylation at promoters, exons and introns was …

DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites

M Krolevets, V Cate, JH Prochaska, A Schulz… - Clinical …, 2023 - Springer
Background Cardiovascular disease (CVD) is the leading cause of death worldwide and
considered one of the most environmentally driven diseases. The role of DNA methylation in …