Resveratrol prevents the development of abdominal aortic aneurysm through attenuation of inflammation, oxidative stress, and neovascularization
OBJECTIVE: We sought to examine the effect of resveratrol (3, 4′, 5-trihydroxy-trans-
stilbene), a plant-derived polyphenolic compound, on the development of abdominal aortic …
stilbene), a plant-derived polyphenolic compound, on the development of abdominal aortic …
Resveratrol counteracts systemic and local inflammation involved in early abdominal aortic aneurysm development
D Palmieri, B Pane, C Barisione, G Spinella… - Journal of Surgical …, 2011 - Elsevier
BACKGROUND: Monocyte activation, macrophage infiltration, vascular oxidative stress and
matrix proteolysis are inflammatory key steps contributing to abdominal aortic aneurysm …
matrix proteolysis are inflammatory key steps contributing to abdominal aortic aneurysm …
Resveratrol inhibits growth of experimental abdominal aortic aneurysm associated with upregulation of angiotensin-converting enzyme 2
Objective—Recent evidence suggests an important role for angiotensin-converting enzyme
2 (ACE2) in limiting abdominal aortic aneurysm (AAA). This study examined the effect of …
2 (ACE2) in limiting abdominal aortic aneurysm (AAA). This study examined the effect of …
Quercetin, a flavonoid with anti-inflammatory activity, suppresses the development of abdominal aortic aneurysms in mice
L Wang, B Wang, H Li, H Lu, F Qiu, L Xiong… - European Journal of …, 2012 - Elsevier
Inflammation has been implicated as a contributing factor in the development of abdominal
aortic aneurysms (AAA). Quercetin, a natural flavonoid with anti-inflammatory properties, is …
aortic aneurysms (AAA). Quercetin, a natural flavonoid with anti-inflammatory properties, is …
[HTML][HTML] Quercetin reduces oxidative stress and inhibits activation of c‑Jun N‑terminal kinase/activator protein‑1 signaling in an experimental mouse model of …
L Wang, X Cheng, H Li, F Qiu… - Molecular …, 2014 - spandidos-publications.com
Oxidative stress is becoming increasingly linked to the pathogenesis of abdominal aortic
aneurysms (AAAs). The antioxidant activity of flavonoids has attracted attention for their …
aneurysms (AAAs). The antioxidant activity of flavonoids has attracted attention for their …
[HTML][HTML] Prevention of abdominal aortic aneurysm progression by oral administration of green tea polyphenol in a rat model
S Setozaki, K Minakata, H Masumoto, S Hirao… - Journal of Vascular …, 2017 - Elsevier
Objective Inflammation-mediated elastin destruction in the aortic medial layer is related to
progression of abdominal aortic aneurysm (AAA). Epigallocatechin-3-gallate (EGCG), a …
progression of abdominal aortic aneurysm (AAA). Epigallocatechin-3-gallate (EGCG), a …
Quercetin Downregulates Cyclooxygenase‐2 Expression and HIF‐1α/VEGF Signaling‐Related Angiogenesis in a Mouse Model of Abdominal Aortic Aneurysm
L Wang, H Wu, L Xiong, X Liu, N Yang… - BioMed Research …, 2020 - Wiley Online Library
Objective. Abdominal aortic aneurysm (AAA) development has been characterized by
increased expression of vascular endothelial growth factor (VEGF), which contributes to …
increased expression of vascular endothelial growth factor (VEGF), which contributes to …
β-Carotene Attenuates Angiotensin II-Induced Aortic Aneurysm by Alleviating Macrophage Recruitment in Apoe−/− Mice
K Gopal, P Nagarajan, J Jedy, AT Raj, SK Gnanaselvi… - Plos one, 2013 - journals.plos.org
Abdominal aortic aneurysm (AAA) is a common chronic degenerative disease characterized
by progressive aortic dilation and rupture. The mechanisms underlying the role of α …
by progressive aortic dilation and rupture. The mechanisms underlying the role of α …
Vitamin D receptor activation reduces angiotensin-II–induced dissecting abdominal aortic aneurysm in apolipoprotein E–knockout mice
S Martorell, L Hueso, H Gonzalez-Navarro… - … and Vascular Biology, 2016 - Am Heart Assoc
Objective—Abdominal aortic aneurysm (AAA) is a vascular disorder characterized by
chronic inflammation of the aortic wall. Low concentrations of vitamin D3 are associated with …
chronic inflammation of the aortic wall. Low concentrations of vitamin D3 are associated with …
Oral administration of diferuloylmethane (curcumin) suppresses proinflammatory cytokines and destructive connective tissue remodeling in experimental abdominal …
FE Parodi, D Mao, TL Ennis, MB Pagano… - Annals of vascular …, 2006 - Springer
Chronic transmural inflammation and proteolytic destruction of medial elastin are key
mechanisms in the development of abdominal aortic aneurysms (AAAs). Diferuloylmethane …
mechanisms in the development of abdominal aortic aneurysms (AAAs). Diferuloylmethane …