Deciphering the epigenetic code: an overview of DNA methylation analysis methods
Significance: Methylation of cytosine in DNA is linked with gene regulation, and this has
profound implications in development, normal biology, and disease conditions in many …
profound implications in development, normal biology, and disease conditions in many …
CpGassoc: an R function for analysis of DNA methylation microarray data
With the increasing availability of high-density methylation microarrays, there has been
growing interest in analysis of DNA methylation data. We have developed CpGassoc, an R …
growing interest in analysis of DNA methylation data. We have developed CpGassoc, an R …
Cytosine methylation profiling of cancer cell lines
DNA-methylation changes in human cancer are complex and vary between the different
types of cancer. Capturing this epigenetic variability in an atlas of DNA-methylation changes …
types of cancer. Capturing this epigenetic variability in an atlas of DNA-methylation changes …
Methodological challenges in constructing DNA methylation risk scores
Polygenic approaches often access more variance of complex traits than is possible by
single variant approaches. For genotype data, genetic risk scores (GRS) are widely used for …
single variant approaches. For genotype data, genetic risk scores (GRS) are widely used for …
Genome-scale DNA methylation analysis
SD Fouse, RP Nagarajan, JF Costello - Epigenomics, 2010 - Taylor & Francis
The haploid human genome contains approximately 29 million CpGs that exist in a
methylated, hydroxymethylated or unmethylated state, collectively referred to as the DNA …
methylated, hydroxymethylated or unmethylated state, collectively referred to as the DNA …
DNA methylation data by sequencing: experimental approaches and recommendations for tools and pipelines for data analysis
I Rauluseviciute, F Drabløs, MB Rye - Clinical epigenetics, 2019 - Springer
Sequencing technologies have changed not only our approaches to classical genetics, but
also the field of epigenetics. Specific methods allow scientists to identify novel genome-wide …
also the field of epigenetics. Specific methods allow scientists to identify novel genome-wide …