Abstract Background Late-onset Alzheimer's disease (AD) is a complex multifactorial
affliction, the pathogenesis of which is thought to involve gene-environment interactions that …

Epigenetic mechanisms, which include DNA methylation, a variety of post-translational
modifications of histone proteins (acetylation, phosphorylation, methylation, ubiquitination …

Aging is a significant risk factor for Alzheimer's disease (AD), although the precise
mechanism and molecular basis of AD are not yet fully understood. Epigenetic mechanisms …

Alzheimer's disease (AD) is the most widespread neurodegenerative disorder and has
caused a major global health concern with the aging of the population. Recent studies have …

Epigenetic processes play a key role in the central nervous system and altered levels of 5-
methylcytosine have been associated with a number of neurologic phenotypes, including …

Background Epigenetic modifications, namely non-coding RNAs, DNA methylation, and
histone modifications such as methylation, phosphorylation, acetylation, ubiquitylation, and …

Mechanisms of epigenetic regulation, including DNA methylation, chromatin remodeling,
and histone post-translational modifications, are involved in multiple aspects of neuronal …

The cytoarchitecture and cellular signaling mechanisms of the nervous system are complex,
and this complexity is reflected at the molecular level with more genes being expressed in …

Cancer is an aging‐associated disease, but the underlying molecular links between these
processes are still largely unknown. Gene promoters that become hypermethylated in aging …

Alzheimer's disease is a progressive neurodegenerative disorder, affecting 50 million
people worldwide, for which there is no cure, or effective treatment. Individuals suffering from …