[HTML][HTML] Genome-wide assessment of differential DNA methylation associated with autoantibody production in systemic lupus erythematosus

SA Chung, J Nititham, E Elboudwarej, HL Quach… - PloS one, 2015 - journals.plos.org
Systemic lupus erythematosus (SLE) is characterized by the development of autoantibodies
associated with specific clinical manifestations. Previous studies have shown an association …

[PDF][PDF] Dynamics of methylation of CpG sites associated with systemic lupus erythematosus subtypes in a longitudinal cohort

CM Lanata, J Nititham, KE Taylor… - Arthritis & …, 2022 - Wiley Online Library
Objective Findings from cross‐sectional studies have revealed associations between DNA
methylation and systemic lupus erythematosus (SLE) outcomes. This study was undertaken …

DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus

J Imgenberg-Kreuz, JC Almlöf, D Leonard… - Annals of the …, 2018 - ard.bmj.com
Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune condition with
heterogeneous presentation and complex aetiology where DNA methylation changes are …

Epigenome-wide association study of peripheral blood mononuclear cells in systemic lupus erythematosus: identifying DNA methylation signatures associated with …

S Joseph, NI George, B Green-Knox, EL Treadwell… - Journal of …, 2019 - Elsevier
Systemic lupus erythematosus (SLE or lupus) is a heterogeneous autoimmune disease
characterized by the involvement of multiple organs and the production of antinuclear …

[HTML][HTML] Shared and unique patterns of DNA methylation in systemic lupus erythematosus and primary Sjögren's syndrome

J Imgenberg-Kreuz, JC Almlöf, D Leonard… - Frontiers in …, 2019 - frontiersin.org
Objectives: To perform a cross-comparative analysis of DNA methylation in patients with
systemic lupus erythematosus (SLE), patients with primary Sjögren's syndrome (pSS), and …

[HTML][HTML] Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes …

DM Absher, X Li, LL Waite, A Gibson, K Roberts… - PLoS …, 2013 - journals.plos.org
Systemic lupus erythematosus (SLE) is an autoimmune disease with known genetic,
epigenetic, and environmental risk factors. To assess the role of DNA methylation in SLE, we …

Epigenetic variability in systemic lupus erythematosus: what we learned from genome-wide DNA methylation studies

M Teruel, AH Sawalha - Current rheumatology reports, 2017 - Springer
Purpose of Review DNA methylation has emerged as an important contributing factor in the
pathogenesis of systemic lupus erythematosus (SLE). Here, we describe the DNA …

Cell lineage-specific genome-wide DNA methylation analysis of patients with paediatric-onset systemic lupus erythematosus

KS Yeung, TL Lee, MY Mok, CCY Mak, W Yang… - Epigenetics, 2019 - Taylor & Francis
Patients with paediatric-onset systemic lupus erythematosus (SLE) often present with more
severe clinical courses than adult-onset patients. Although genome-wide DNA methylation …

[HTML][HTML] Genome-wide DNA methylation analysis of Chinese patients with systemic lupus erythematosus identified hypomethylation in genes related to the type I …

KS Yeung, BHY Chung, S Choufani, MY Mok… - PLoS …, 2017 - journals.plos.org
Background Epigenetic variants have been shown in recent studies to be important
contributors to the pathogenesis of systemic lupus erythematosus (SLE). Here, we report a 2 …

Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus

M Jeffries, M Dozmorov, Y Tang, JT Merrill, JD Wren… - Epigenetics, 2011 - Taylor & Francis
Systemic lupus erythematosus is a chronic-relapsing autoimmune disease of incompletely
understood etiology. Recent evidence strongly supports an epigenetic contribution to the …