Proteins secreted by the fungal pathogen Cryptococcus neoformans may be involved in
invasion and could be useful in vaccine design. Despite the medical importance of this …

The virulence of Cryptococcus neoformans isolates with high and low extracellular
proteolytic activity was investigated in mice. No consistent relationship between proteolytic …

Cryptococcus neoformans is an opportunistic fungal pathogen that may lead to life-
threatening meningoencephalitis and pulmonary infections in immunosuppressed hosts …

A 115-kDa exoantigen produced by Cryptococcus neoformans recognized by the previously
described murine monoclonal antibody 7C9 has been purified from culture filtrate by a …

Three monoclonal antibodies (MAbs), all of the immunoglobulin G1 subclass, were raised
against Cryptococcus neoformans by using the technique of cyclophosphamide ablation of …

Cryptococcus neoformans is a major fungal pathogen for patients with debilitated immune
systems. However, no information is available on the stability of virulence or of phenotypes …

We compared a cryptococcal culture filtrate antigen referred to as CneF with chemically
defined cryptococcal antigen fractions isolated by Cherniak and co-workers by using double …

The efficacy of monoclonal antibody (MAb 2H1) against diverse strains of Cryptococcus
neoformans was studied in a murine model of intravenous infection. For six of eight strains …

Two virulent strains of Cryptococcus neoformans and two nonvirulent forms (C. albidus and
C. laurentii) were grown in liquid culture to produce maximal capsule formation. A …

Three monoclonal antibodies (MAbs), designated 7C5, 7C9, and 5G8, against a cytoplasmic
antigen of Cryptococcus neoformans were produced. MAbs 7C5 and 7C9 recognize culture …