Infectious microorganisms often play a role in modulating the immune responses of their
infected hosts. We demonstrate that Cryptococcus neoformans signals through the Rim101 …

Cryptococcus neoformans is a prevalent human fungal pathogen that must survive within
various tissues in order to establish a human infection. We have identified the C …

The Rim101 protein is a conserved pH-responsive transcription factor that mediates
important interactions between several fungal pathogens and the infected host. In the …

Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills over
600,000 people annually. Here, we report integrated computational and experimental …

The Cryptococcus neoformans NRG1 gene was identified using gene microarrays to define
putative transcription factor genes regulated by the cyclic AMP (cAMP) signal transduction …

Compared to other fungal pathogens, Cryptococcus neoformans is particularly adept at
avoiding detection by innate immune cells. To explore fungal cellular features involved in …

Cryptococcus neoformans is a fungal pathogen of immunocompromised people that causes
fatal meningitis. The fungal cell wall is essential to viability and pathogenesis of C …

The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

Cryptococcus neoformans is an encapsulated opportunistic organism that can undergo
phenotypic switching. In this process, the parent smooth colony (SM) switches to a more …

Macrophages serve as a first line of defense against infection with the facultative
intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate …