CpG methylation is known to suppress transcription. This repression is generally thought to
be related to alterations of chromatin structure that are specified by the methylation. The …

CpG DNA methylation has previously been correlated with the suppression of transcription.
The mechanism of this suppression is not understood, and many aspects of the temporal …

Transcriptional repression by méthylation of CpG Page 1 Journal of Cell Science, Supplement
16, 9-14 (1992) Printed in Great Britain © The Company of Biologists Limited 1992 9 …

The three-way connection between DNA methylation, gene activity and chromatin structure
has been known for almost two decades. Nevertheless, the molecular link between methyl …

Repression of transcription from densely methylated genes can be mediated by the methyl‐
CpG binding protein MeCP‐1 (Boyes and Bird, 1991). Here we have investigated the effect …

One of the mechanisms proposed to explain how CpG methylation effects gene repression
invokes a DNA methylation-determined chromatin structure. Previous work implied that this …

We have developed a strategy to introduce in vitro-methylated DNA into defined
chromosomal locations. Using this system, we examined the effects of methylation on …

DNA methylation is commonly associated with gene silencing, and a link between histone
deacetylation and DNA methylation has been established. However, the transcriptional …

The methylation of CpG islands is often equated with transcriptional inactivity and there is
overwhelming evidence that this is the case for islands located in gene promoters. Such …

An important consequence of CpG methylation is the local silencing of gene expression. In
part this can be mediated by direct interference of methylation with the binding of …