[HTML][HTML] Flavonoids showed anticancer effects on the ovarian cancer cells: Involvement of reactive oxygen species, apoptosis, cell cycle and invasion

Z Tavsan, HA Kayali - Biomedicine & pharmacotherapy, 2019 - Elsevier
Flavonoids have been recently identified as a potential anticancer agent against various
human epithelial cancers. In this study, the elucidation of mechanisms underlying the …

Kaempferol enhances cisplatin's effect on ovarian cancer cells through promoting apoptosis caused by down regulation of cMyc

H Luo, MK Daddysman, GO Rankin, BH Jiang… - Cancer cell …, 2010 - Springer
Background Ovarian cancer is one of the most significant malignancies in the western world.
Studies showed that Ovarian cancers tend to grow resistance to cisplatin treatment …

Low concentration of quercetin antagonizes the cytotoxic effects of anti-neoplastic drugs in ovarian cancer

N Li, C Sun, B Zhou, H Xing, D Ma, G Chen, D Weng - PLoS One, 2014 - journals.plos.org
Objective The role of Quercetin in ovarian cancer treatment remains controversial, and the
mechanism is unknown. The aim of this study was to investigate the therapeutic effects of …

Resveratrol inhibits the proliferation and induces the apoptosis in ovarian cancer cells via inhibiting glycolysis and targeting AMPK/mTOR signaling pathway

Y Liu, L Tong, Y Luo, X Li, G Chen… - Journal of cellular …, 2018 - Wiley Online Library
Aerobic glycolysis is an important metabolic rewiring in cancer cells to promote glucose
uptake and lactate production, and targeting aerobic glycolysis becomes a promising …

Inhibition of cell growth and VEGF expression in ovarian cancer cells by flavonoids

H Luo, BH Jiang, SM King, YC Chen - Nutrition and cancer, 2008 - Taylor & Francis
Dietary flavonoids have been shown to be protective against various types of cancers. Here
we studied the effects of 12 different flavonoids and other substances on cell proliferation …

Quercetin inhibits human metastatic ovarian cancer cell growth and modulates components of the intrinsic apoptotic pathway in PA-1 cell line

D Teekaraman, SP Elayapillai, MP Viswanathan… - Chemico-biological …, 2019 - Elsevier
Ovarian cancer is the leading cause of gynaecology related cancer death worldwide. It is
often diagnosed with an advanced stage. Apoptosis is a process of programmed cell death …

Quercetin: a natural compound for ovarian cancer treatment

R Shafabakhsh, Z Asemi - Journal of ovarian research, 2019 - Springer
Ovarian cancer is the main cause of death among all reproductive cancers in females. In
2018, ovarian cancer was the seventh most common cancer of women entire the world. A …

Apigenin, a dietary flavonoid, inhibits proliferation of human bladder cancer T-24 cells via blocking cell cycle progression and inducing apoptosis

MD Shi, CK Shiao, YC Lee, YW Shih - Cancer cell international, 2015 - Springer
Background Apigenin is a nontoxic dietary flavonoid, and it may have chemopreventive and
therapeutic potential as an anti-inflammatory, antioxidant, and anti-cancer agent. However …

Resveratrol induces immunogenic cell death of human and murine ovarian carcinoma cells

Y Zhang, S Yang, Y Yang, T Liu - Infectious agents and cancer, 2019 - Springer
Purpose This study aimed to clarify whether immunogenic cell death (ICD) contributed to the
anti-tumor action of resveratrol against ovarian carcinoma. Methods Resveratrol suppressed …

Apigenin inhibits VEGF and HIF‐1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways

J Fang, C Xia, Z Cao, JZ Zheng, E Reed… - The FASEB …, 2005 - Wiley Online Library
Apigenin is a nontoxic dietary flavonoid that has been shown to possess anti‐tumor
properties and therefore poses special interest for the development of a novel …