Non-CG methylation in the human genome
DNA methylation is a chemical modification that occurs predominantly on CG dinucleotides
in mammalian genomes. However, recent studies have revealed that non-CG methylation …
in mammalian genomes. However, recent studies have revealed that non-CG methylation …
CpG methylation recruits sequence specific transcription factors essential for tissue specific gene expression
R Chatterjee, C Vinson - Biochimica et Biophysica Acta (BBA)-Gene …, 2012 - Elsevier
CG methylation is an epigenetically inherited chemical modification of DNA found in plants
and animals. In mammals it is essential for accurate regulation of gene expression and …
and animals. In mammals it is essential for accurate regulation of gene expression and …
A unique role for DNA (hydroxy) methylation in epigenetic regulation of human inhibitory neurons
Brain function depends on interaction of diverse cell types whose gene expression and
identity are defined, in part, by epigenetic mechanisms. Neuronal DNA contains two major …
identity are defined, in part, by epigenetic mechanisms. Neuronal DNA contains two major …
Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites
A Kozlenkov, P Roussos, A Timashpolsky… - Nucleic acids …, 2014 - academic.oup.com
Abstract We applied Illumina Human Methylation450K array to perform a genomic-scale
single-site resolution DNA methylation analysis in neuronal and nonneuronal (primarily …
single-site resolution DNA methylation analysis in neuronal and nonneuronal (primarily …
Mammalian non-CpG methylation: stem cells and beyond
SE Pinney - Biology, 2014 - mdpi.com
Although CpG dinucleotides remain the primary site for DNA methylation in mammals, there
is emerging evidence that DNA methylation at non-CpG sites (CpA, CpT and CpC) is not …
is emerging evidence that DNA methylation at non-CpG sites (CpA, CpT and CpC) is not …
[HTML][HTML] Formation of methylation patterns in the mammalian genome
MS Turker, TH Bestor - Mutation Research/Reviews in Mutation Research, 1997 - Elsevier
Cytosine methylation in mammals is an epigenetic modification required for viability of the
developing embryo. It has been suggested that DNA methylation plays important roles in X …
developing embryo. It has been suggested that DNA methylation plays important roles in X …
DNA methylation and human disease
KD Robertson - Nature Reviews Genetics, 2005 - nature.com
DNA methylation is a crucial epigenetic modification of the genome that is involved in
regulating many cellular processes. These include embryonic development, transcription …
regulating many cellular processes. These include embryonic development, transcription …
CpG and non-CpG methylation in epigenetic gene regulation and brain function
HS Jang, WJ Shin, JE Lee, JT Do - Genes, 2017 - mdpi.com
DNA methylation is a major epigenetic mark with important roles in genetic regulation.
Methylated cytosines are found primarily at CpG dinucleotides, but are also found at non …
Methylated cytosines are found primarily at CpG dinucleotides, but are also found at non …
[HTML][HTML] DNA methylation signatures within the human brain
C Ladd-Acosta, J Pevsner, S Sabunciyan… - The American Journal of …, 2007 - cell.com
DNA methylation is a heritable modification of genomic DNA central to development,
imprinting, transcriptional regulation, chromatin structure, and overall genomic stability …
imprinting, transcriptional regulation, chromatin structure, and overall genomic stability …
Global epigenomic reconfiguration during mammalian brain development
Introduction Several lines of evidence point to a key role for dynamic epigenetic changes
during brain development, maturation, and learning. DNA methylation (mC) is a stable …
during brain development, maturation, and learning. DNA methylation (mC) is a stable …