Zebrafish (Danio rerio) is a vertebrate model organism that is widely used for studying a
plethora of biological questions, including developmental processes, effects of external cues …

The DNA methylation landscape is dynamically patterned during development and distinct
methylation patterns distinguish healthy from diseased cells. However, whether tissue …

Genome-wide DNA methylation mapping uncovers epigenetic changes associated with
animal development, environmental adaptation, and species evolution. To address the lack …

Reduced representation bisulfite sequencing (RRBS) has been used to profile DNA
methylation patterns in mammalian genomes such as human, mouse and rat. The …

Genomic DNA methylation functions to repress gene expression by interfering with
transcription factor binding and/or recruiting repressive chromatin machinery. Recent data …

DNA methylation plays crucial roles during embryonic development. Here we present
MethBank (http://dnamethylome. org), a DNA methylome programming database that …

DNA methylation is an epigenetic mark associated with transcriptional repression and
essential for proper vertebrate development. Because of its association with human …

DNA methylation is crucial for normal development and cellular differentiation in many large-
genome eukaryotes. The small tropical freshwater fish Danio rerio (zebrafish) has recently …

DNA methylation on cytosine in vertebrates such as zebrafish serves to silence gene
expression by interfering with the binding of certain transcription factors and through the …

Methylation of cytosines in the CG context (mCG) is the most abundant DNA modification in
vertebrates that plays crucial roles in cellular differentiation and identity. After fertilization …