Identification of the gene signature reflecting schizophrenia's etiology by constructing artificial intelligence‐based method of enhanced reproducibility
Aims As one of the most fundamental questions in modern science,“what causes
schizophrenia (SZ)” remains a profound mystery due to the absence of objective gene …
schizophrenia (SZ)” remains a profound mystery due to the absence of objective gene …
Consistent gene signature of schizophrenia identified by a novel feature selection strategy from comprehensive sets of transcriptomic data
The etiology of schizophrenia (SCZ) is regarded as one of the most fundamental puzzles in
current medical research, and its diagnosis is limited by the lack of objective molecular …
current medical research, and its diagnosis is limited by the lack of objective molecular …
Gene-and evidence-based candidate gene selection for schizophrenia and gene feature analysis
OBJECTIVE: Schizophrenia is a chronic psychiatric disorder that affects about 1% of the
population globally. A tremendous amount of effort has been expended in the past decade …
population globally. A tremendous amount of effort has been expended in the past decade …
Schizophrenia gene networks and pathways and their applications for novel candidate gene selection
Background Schizophrenia (SZ) is a heritable, complex mental disorder. We have seen
limited success in finding causal genes for schizophrenia from numerous conventional …
limited success in finding causal genes for schizophrenia from numerous conventional …
Hypothesis-driven candidate genes for schizophrenia compared to genome-wide association results
AL Collins, Y Kim, P Sklar, MC O'Donovan… - Psychological …, 2012 - cambridge.org
BackgroundCandidate gene studies have been a key approach to the genetics of
schizophrenia (SCZ). However, the results of these studies are confusing and no genes …
schizophrenia (SCZ). However, the results of these studies are confusing and no genes …
SZDB: a database for schizophrenia genetic research
Y Wu, YG Yao, XJ Luo - Schizophrenia bulletin, 2017 - academic.oup.com
Schizophrenia (SZ) is a debilitating brain disorder with a complex genetic architecture.
Genetic studies, especially recent genome-wide association studies (GWAS), have identified …
Genetic studies, especially recent genome-wide association studies (GWAS), have identified …
Mega-analysis of odds ratio: a convergent method for a deep understanding of the genetic evidence in schizophrenia
Numerous high-throughput omics studies have been conducted in schizophrenia, providing
an accumulated catalog of susceptible variants and genes. The results from these studies …
an accumulated catalog of susceptible variants and genes. The results from these studies …
Mapping the schizophrenia genes by neuroimaging: the opportunities and the challenges
A Arslan - International Journal of Molecular Sciences, 2018 - mdpi.com
Schizophrenia (SZ) is a heritable brain disease originating from a complex interaction of
genetic and environmental factors. The genes underpinning the neurobiology of SZ are …
genetic and environmental factors. The genes underpinning the neurobiology of SZ are …
Machine learning in schizophrenia genomics, a case‐control study using 5,090 exomes
Our hypothesis is that machine learning (ML) analysis of whole exome sequencing (WES)
data can be used to identify individuals at high risk for schizophrenia (SCZ). This study …
data can be used to identify individuals at high risk for schizophrenia (SCZ). This study …
Leveraging genome-wide association and clinical data in revealing schizophrenia subgroups
Schizophrenia (SCZ) has long been recognized as a highly heterogeneous disorder.
Patients differed in their clinical manifestations, prognosis, and underlying …
Patients differed in their clinical manifestations, prognosis, and underlying …