Background Although the association between diet and disease is well documented, the
biologic mechanisms involved have not been entirely elucidated. In this study, we evaluate …

At an international level, colorectal cancer (CRC) is a major cause of morbidity and mortality.
Diet plays a major etiologic role, and a range of putative dietary carcinogens have been …

Gastrointestinal cancers account for 20% of all cancer incidences worldwide. Colorectal
cancer is the second most common cause of all cancer-related mortality and is increasing in …

Several diet and lifestyle factors may impact health by influencing oxidative stress levels. We
hypothesize that level of cigarette smoking, alcohol, anti-inflammatory drugs, and diet alter …

Colon cancer is the fourth most common diagnosed cancer in the USA. The American
Cancer Society estimates that it will account in 2006 for almost 150,000 cases and over …

Mouse genetic models that probe important pathways in intestinal cell maturation, such as
cell-cycle regulation, apoptosis, and, especially, lineage specific differentiation, have …

Increasingly, the gut microbiome is implicated in the etiology of cancer, not only as an
infectious agent but also by altering exposure to dietary compounds that influence disease …

Background Previous epidemiological studies have found a link between colorectal cancer
(CRC) and human dietary habits. However, the inherent limitations and inevitable …

Evidence continues to implicate dietary components and genetic susceptibilities as
important determinants of cancer risk and tumor behavior. Variation in cancer incidence …

The field of nutrition research has traditionally focused on the effects of macronutrients and
micronutrients on the body. However, it has become evident that individuals have unique …