Dietary intake alters gene expression in colon tissue: possible underlying mechanism for the influence of diet on disease
AJ Pellatt, ML Slattery, LE Mullany… - Pharmacogenetics …, 2016 - journals.lww.com
Background Although the association between diet and disease is well documented, the
biologic mechanisms involved have not been entirely elucidated. In this study, we evaluate …
biologic mechanisms involved have not been entirely elucidated. In this study, we evaluate …
[HTML][HTML] Recent advances in understanding of interactions between genes and diet in the etiology of colorectal cancer
LR Ferguson - World Journal of Gastrointestinal Oncology, 2010 - ncbi.nlm.nih.gov
At an international level, colorectal cancer (CRC) is a major cause of morbidity and mortality.
Diet plays a major etiologic role, and a range of putative dietary carcinogens have been …
Diet plays a major etiologic role, and a range of putative dietary carcinogens have been …
Convergence of genetic, nutritional and inflammatory factors in gastrointestinal cancers
AJ MacFarlane, PJ Stover - Nutrition reviews, 2007 - academic.oup.com
Gastrointestinal cancers account for 20% of all cancer incidences worldwide. Colorectal
cancer is the second most common cause of all cancer-related mortality and is increasing in …
cancer is the second most common cause of all cancer-related mortality and is increasing in …
Differential gene expression in colon tissue associated with diet, lifestyle, and related oxidative stress
ML Slattery, DF Pellatt, LE Mullany, RK Wolff - PLoS One, 2015 - journals.plos.org
Several diet and lifestyle factors may impact health by influencing oxidative stress levels. We
hypothesize that level of cigarette smoking, alcohol, anti-inflammatory drugs, and diet alter …
hypothesize that level of cigarette smoking, alcohol, anti-inflammatory drugs, and diet alter …
Nutrigenomics and the prevention of colon cancer
CD Davis - Pharmacogenomics, 2007 - Taylor & Francis
Colon cancer is the fourth most common diagnosed cancer in the USA. The American
Cancer Society estimates that it will account in 2006 for almost 150,000 cases and over …
Cancer Society estimates that it will account in 2006 for almost 150,000 cases and over …
[HTML][HTML] Dietary components modify gene expression: implications for carcinogenesis
K Yang, WC Yang, J Mariadason, A Velcich… - The Journal of …, 2005 - Elsevier
Mouse genetic models that probe important pathways in intestinal cell maturation, such as
cell-cycle regulation, apoptosis, and, especially, lineage specific differentiation, have …
cell-cycle regulation, apoptosis, and, especially, lineage specific differentiation, have …
Diet, the gut microbiome, and epigenetics
MAJ Hullar, BC Fu - The Cancer Journal, 2014 - journals.lww.com
Increasingly, the gut microbiome is implicated in the etiology of cancer, not only as an
infectious agent but also by altering exposure to dietary compounds that influence disease …
infectious agent but also by altering exposure to dietary compounds that influence disease …
Causal associations between dietary factors and colorectal cancer risk: a Mendelian randomization study
X Zhang, Z Wu, X Wang, B Xin, P Hu, Y Yin, S He… - Frontiers in …, 2024 - frontiersin.org
Background Previous epidemiological studies have found a link between colorectal cancer
(CRC) and human dietary habits. However, the inherent limitations and inevitable …
(CRC) and human dietary habits. However, the inherent limitations and inevitable …
[HTML][HTML] Nutritional “omics” technologies for elucidating the role (s) of bioactive food components in colon cancer prevention
CD Davis, NG Hord - The Journal of nutrition, 2005 - Elsevier
Evidence continues to implicate dietary components and genetic susceptibilities as
important determinants of cancer risk and tumor behavior. Variation in cancer incidence …
important determinants of cancer risk and tumor behavior. Variation in cancer incidence …
Genetics, Nutrition, and Health: A New Frontier in Disease Prevention
The field of nutrition research has traditionally focused on the effects of macronutrients and
micronutrients on the body. However, it has become evident that individuals have unique …
micronutrients on the body. However, it has become evident that individuals have unique …
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