Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP
NT Crump, CA Hazzalin, EM Bowers… - Proceedings of the …, 2011 - National Acad Sciences
Histone modifications are reported to show different behaviors, associations, and functions
in different genomic niches and organisms. We show here that rapid, continuous turnover of …
in different genomic niches and organisms. We show here that rapid, continuous turnover of …
[HTML][HTML] Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly
SC Sampath, I Marazzi, KL Yap, SC Sampath… - Molecular cell, 2007 - cell.com
Epigenetic gene silencing in eukaryotes is regulated in part by lysine methylation of the core
histone proteins. While histone lysine methylation is known to control gene expression …
histone proteins. While histone lysine methylation is known to control gene expression …
[HTML][HTML] Understanding the relationship between DNA methylation and histone lysine methylation
DNA methylation acts as an epigenetic modification in vertebrate DNA. Recently it has
become clear that the DNA and histone lysine methylation systems are highly interrelated …
become clear that the DNA and histone lysine methylation systems are highly interrelated …
DNA methylation pathways and their crosstalk with histone methylation
J Du, LM Johnson, SE Jacobsen… - Nature reviews Molecular …, 2015 - nature.com
Methylation of DNA and of histone 3 at Lys 9 (H3K9) are highly correlated with gene
silencing in eukaryotes from fungi to humans. Both of these epigenetic marks need to be …
silencing in eukaryotes from fungi to humans. Both of these epigenetic marks need to be …
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
Y Zhang, D Reinberg - Genes & development, 2001 - genesdev.cshlp.org
In this review, we discuss recent advances made on histone methylation and its diverse
functions in regulating gene expression. Methylation of histone polypeptides might be static …
functions in regulating gene expression. Methylation of histone polypeptides might be static …
[HTML][HTML] Histone H4-lysine 20 monomethylation is increased in promoter and coding regions of active genes and correlates with hyperacetylation
H Talasz, HH Lindner, B Sarg, W Helliger - Journal of Biological Chemistry, 2005 - ASBMB
Methylation and acetylation of position-specific lysine residues in the N-terminal tail of
histones H3 and H4 play an important role in regulating chromatin structure and function. In …
histones H3 and H4 play an important role in regulating chromatin structure and function. In …
Histone methylation in transcriptional control
T Kouzarides - Current opinion in genetics & development, 2002 - Elsevier
Over the past year or so, methylation of histones has come to be recognised as a major
player in the regulation of gene activity. This notion follows the discovery of lysine and …
player in the regulation of gene activity. This notion follows the discovery of lysine and …
Tug of war: adding and removing histone lysine methylation in Arabidopsis
Highlights•Genome wide distribution and function of H3K4, K27, K36me in plant and
animal.•Summary of histone lysine methylation writer, eraser and reader in plant and …
animal.•Summary of histone lysine methylation writer, eraser and reader in plant and …
[HTML][HTML] Epigenetic regulation of development by histone lysine methylation
S Dambacher, M Hahn, G Schotta - Heredity, 2010 - nature.com
Epigenetic mechanisms contribute to the establishment and maintenance of cell-type-
specific gene expression patterns. In this review, we focus on the functions of histone lysine …
specific gene expression patterns. In this review, we focus on the functions of histone lysine …
Epigenetic regulation by histone methylation and histone variants
P Cheung, P Lau - Molecular endocrinology, 2005 - academic.oup.com
Epigenetics is the study of heritable changes in gene expression that are not mediated at the
DNA sequence level. Molecular mechanisms that mediate epigenetic regulation include …
DNA sequence level. Molecular mechanisms that mediate epigenetic regulation include …