[HTML][HTML] Serum-based DNA methylation biomarkers in colorectal cancer: potential for screening and early detection

T Summers, RC Langan, A Nissan… - Journal of …, 2013 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common cause of cancer-related death in the
United States. Early identification and treatment of pre-cancerous colorectal lesions, or node …

DNA methylation biomarkers of stool and blood for early detection of colon cancer

L Hong, N Ahuja - Genetic testing and molecular biomarkers, 2013 - liebertpub.com
Detection of colorectal cancer at an early stage may significantly decrease mortality from the
disease. The current screening test of colonoscopy is of high efficacy, but its acceptance in …

Review of blood-based colorectal cancer screening: how far are circulating cell-free DNA methylation markers from clinical implementation?

MBW Ørntoft - Clinical colorectal cancer, 2018 - Elsevier
Colorectal cancer (CRC) is a leading cause of cancer related deaths worldwide, and late
stages (III-IV) in particular have low 5-year survival rates. Stage shifting by CRC screening …

DNA methylation biomarkers in colorectal cancer: Clinical applications for precision medicine

N Fatemi, S Tierling, HA Es, M Varkiani… - … journal of cancer, 2022 - Wiley Online Library
Colorectal cancer (CRC) is the second leading cause of cancer death worldwide that is
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …

DNA methylation markers detected in blood, stool, urine, and tissue in colorectal cancer: a systematic review of paired samples

EA Laugsand, SS Brenne, F Skorpen - International Journal of Colorectal …, 2021 - Springer
Purpose Methylated cell-free DNA in liquid biopsies are promising non-invasive biomarkers
for colorectal cancer (CRC). Optimal markers would have high sensitivity and specificity for …

[HTML][HTML] Abnormal DNA methylation as a cell-free circulating DNA biomarker for colorectal cancer detection: A review of literature

M Galanopoulos, N Tsoukalas… - World journal of …, 2017 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most prevalent malignancies in the world. CRC-
associated morbidity and mortality is continuously increasing, in part due to a lack of early …

Promising epigenetic biomarkers for the early detection of colorectal cancer: a systematic review

SA Anghel, CB Ioniță-Mîndrican, I Luca, AL Pop - Cancers, 2021 - mdpi.com
Simple Summary High-performance, non-invasive screening is a requirement in colorectal
cancer (CRC) as early detection is a key in reducing disease-related mortality in CRC …

DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer

FJ Carmona, D Azuara, A Berenguer-Llergo… - Cancer prevention …, 2013 - AACR
DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer (CRC) and
precursor lesions have been extensively studied. Different panels have been reported …

DNA methylation patterns as noninvasive biomarkers and targets of epigenetic therapies in colorectal cancer

Y Hashimoto, TJ Zumwalt, A Goel - Epigenomics, 2016 - Taylor & Francis
Aberrant DNA methylation is frequently detected in gastrointestinal tumors, and can
therefore potentially be used to screen, diagnose, prognosticate, and predict colorectal …

Hypermethylated DNA, a circulating biomarker for colorectal cancer detection

SL Rasmussen, HB Krarup, KG Sunesen… - PLoS …, 2017 - journals.plos.org
Background Colorectal cancer (CRC) is one of the most common cancers in the western
world. Screening is an efficient method of reducing cancer-related mortality. Molecular …