Nonsteroidal antiinflammatory drugs are associated with increased aortic stiffness
M Claridge, S Hobbs, C Quick, N Day… - Vascular health and …, 2005 - Taylor & Francis
Objectives Nonsteroidal antiinflammatory drugs (NSAIDS) have been shown to retard
aneurysm growth in animal models. In vitro studies have shown an inhibitory effect of …
aneurysm growth in animal models. In vitro studies have shown an inhibitory effect of …
Therapeutic modulation of aortic stiffness
AM Hussein, G Shaaya, R Arora… - American Journal of …, 2016 - journals.lww.com
Aortic stiffness (AS) is an important predictor of cardiovascular morbidity in humans. The
present review discusses the possible pathophysiological mechanisms of AS and focuses …
present review discusses the possible pathophysiological mechanisms of AS and focuses …
Simvastatin prevents inflammation‐induced aortic stiffening and endothelial dysfunction
SML Wallace, KM Mäki‐Petäjä… - British journal of …, 2010 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• Both acute and chronic inflammation
are associated with aortic stiffening and endothelial dysfunction.• Statins have been shown …
are associated with aortic stiffening and endothelial dysfunction.• Statins have been shown …
Are antihypertensive drugs associated with abdominal aortic aneurysms?
ABM Wilmink, A Katerina, NE Day, HA Ashton… - Journal of vascular …, 2002 - Elsevier
Objective: The aim of this study was to investigate the association between anti-hypertensive
drugs, the risk of developing an abdominal aortic aneurysm (AAA), aortic wall stiffness …
drugs, the risk of developing an abdominal aortic aneurysm (AAA), aortic wall stiffness …
Anti-inflammatory drugs and statins for arterial stiffness reduction
KM Maki-Petaja, IB Wilkinson - Current pharmaceutical design, 2009 - ingentaconnect.com
Arterial stiffness is a powerful predictor of cardiovascular outcome in various patient groups
as well as in general population, and can directly accelerate the atherosclerotic process …
as well as in general population, and can directly accelerate the atherosclerotic process …
The relationship between abdominal aortic aneurysm distensibility and serum markers of elastin and collagen metabolism
KA Wilson, JS Lindholt, PR Hoskins… - European journal of …, 2001 - Elsevier
Background: abdominal aortic aneurysm (AAA) distensibility may be an independent
predictor of growth and rupture, possibly because it reflects changes in aortic wall structure …
predictor of growth and rupture, possibly because it reflects changes in aortic wall structure …
Arterial stiffness and novel biomarkers in patients with abdominal aortic aneurysms
NPE Kadoglou, I Papadakis, KG Moulakakis… - Regulatory peptides, 2012 - Elsevier
OBJECTIVES: Pulse wave velocity (PWV) constitutes a valid index of arterial stiffness
osteoprotegerin (OPG) and osteopontin (OPN) which are well-established vascular …
osteoprotegerin (OPG) and osteopontin (OPN) which are well-established vascular …
Tumor necrosis factor-α antagonists improve aortic stiffness in patients with inflammatory arthropathies: a controlled study
K Angel, SA Provan, HL Gulseth, P Mowinckel… - …, 2010 - Am Heart Assoc
The chronic inflammatory state of rheumatoid arthritis and other inflammatory arthropathies,
such as ankylosing spondylitis and psoriatic arthritis, contributes to the accelerated …
such as ankylosing spondylitis and psoriatic arthritis, contributes to the accelerated …
Aortic stiffness and disease: location is key
PJ Chowienczyk - Circulation, 2015 - Am Heart Assoc
The study of Raaz and colleagues undoubtedly demonstrates that axial gradients in stiffness
may contribute to AAA formation. However, the most notable finding from this study is the …
may contribute to AAA formation. However, the most notable finding from this study is the …
Inflammation and large arteries: Potential mechanisms for inflammation-induced arterial stiffness
KM Mäki-Petäjä, IB Wilkinson - Artery Research, 2012 - Elsevier
Systemic inflammatory conditions are associated with an increased risk of cardiovascular
disease (CVD). How exactly inflammation leads to this is not fully understood, but it has …
disease (CVD). How exactly inflammation leads to this is not fully understood, but it has …