Performance evaluation of stool DNA methylation tests in colorectal cancer screening: a systematic review and meta‐analysis

M Gachabayov, E Lebovics, A Rojas… - Colorectal …, 2021 - Wiley Online Library
Aim There is not sufficient evidence about whether stool DNA methylation tests allow
prioritizing patients to colonoscopy. Due to the COVID‐19 pandemic, there will be a wait‐list …

[HTML][HTML] The importance of stool DNA methylation in colorectal cancer diagnosis: A meta-analysis

A Mojtabanezhad Shariatpanahi, M Yassi, M Nouraie… - PLoS …, 2018 - journals.plos.org
A large number of tumor-related methylated genes have been suggested to be of diagnostic
and prognostic values for CRC when analyzed in patients' stool samples; however, reported …

[HTML][HTML] The diagnostic value of DNA hypermethylation in stool for colorectal cancer: a meta-analysis

LY Qian, W Zhang - Journal of Cancer Research and …, 2014 - journals.lww.com
Objective: We performed this meta-analysis to document the diagnostic performance of DNA
hypermethylation in stool for colorectal cancer (CRC). Materials and Methods: Relevant …

[HTML][HTML] Colorectal cancer screening using a stool DNA-based SDC2 methylation test: a multicenter, prospective trial

CW Kim, H Kim, HR Kim, BH Kye, HJ Kim, BS Min… - BMC …, 2021 - Springer
Background Prevention and early detection of colorectal cancer (CRC) is a global priority,
with many countries conducting population-based CRC screening programs. Although …

[HTML][HTML] Robust performance of a novel stool DNA test of methylated SDC2 for colorectal cancer detection: a multicenter clinical study

J Wang, S Liu, H Wang, L Zheng, C Zhou, G Li… - Clinical …, 2020 - Springer
Abstract Background and Aims Stool DNA testing is an emerging and attractive option for
colorectal cancer (CRC) screening. We previously evaluated the feasibility of a stool DNA …

[HTML][HTML] Stool DNA methylation assays in colorectal cancer screening

T Kadiyska, A Nossikoff - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is fourth most common cancer in men and third in women
worldwide. Developing a diagnostic panel of sensitive and specific biomarkers for the early …

[HTML][HTML] Lessons from a systematic literature search on diagnostic DNA methylation biomarkers for colorectal cancer: how to increase research value and decrease …

Z Feng, CJG Oberije, AJP van de Wetering… - Clinical and …, 2022 - journals.lww.com
OBJECTIVES: To improve colorectal cancer (CRC) survival and lower incidence rates,
colonoscopy and/or fecal immunochemical test screening are widely implemented. Although …

Noninvasive DNA methylation biomarkers in colorectal cancer: a systematic review

M Xue, SC Lai, ZP Xu, LJ Wang - Journal of digestive diseases, 2015 - Wiley Online Library
Objective To summarize the current evidence on the biomarkers associated with DNA
methylation in the screening and diagnosis of colorectal cancer (CRC). Methods A literature …

Diagnostic value of aberrant gene methylation in stool samples for colorectal cancer or adenomas: a meta-analysis.

Y Yuan, B Qu, J Yan, H Wang, L Yin, Q Han - Panminerva medica, 2014 - europepmc.org
Aim Many studies have reported detection of aberrant methylation of genes in stool sample
for early colorectal cancer (CRC) or adenomas had high sensitivity and specificity, but still …

[HTML][HTML] Fecal DNA methylation markers for detecting stages of colorectal cancer and its precursors: a systematic review

JR Raut, Z Guan, P Schrotz-King, H Brenner - Clinical Epigenetics, 2020 - Springer
Background DNA methylation biomarkers in stool may have applications in early colorectal
cancer (CRC) detection; however, their association with stages of CRC carcinogenesis or …