Major histocompatibility complex II (MHC II) molecules play a vital role in the onset and
control of cellular immunity. In a highly selective process, MHC II presents peptides derived …

Abstract LC–MS/MS has become the standard platform for the characterization of
immunopeptidomes, the collection of peptides naturally presented by major …

Background Computational scanning of peptide candidates that bind to a specific major
histocompatibility complex (MHC) can speed up the peptide-based vaccine development …

Predicting the binding of peptide and major histocompatibility complex (MHC) plays a vital
role in immunotherapy for cancer. The success of Alphafold of applying natural language …

The set of peptides presented on a cell's surface by MHC molecules is known as the
immunopeptidome. Current mass spectrometry technologies allow for identification of large …

Background Binding of peptides to MHC class I molecules (MHC-I) is essential for antigen
presentation to cytotoxic T-cells. Results Here, we demonstrate how a simple alignment step …

Motivation Computationally predicting major histocompatibility complex class I (MHC-I)
peptide binding affinity is an important problem in immunological bioinformatics, which is …

Introduction The comprehensive collection of peptides presented by major histocompatibility
complex (MHC) molecules on the cell surface is collectively known as the …

The identification of MHC class II restricted peptide epitopes is an important goal in
immunological research. A number of computational tools have been developed for this …

Peptide-major histocompatibility complex I (MHC I) binding affinity prediction is crucial for
vaccine development, but existing methods face limitations such as small datasets, model …