EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology
PA Reche, H Zhang, JP Glutting, EL Reinherz - Bioinformatics, 2005 - academic.oup.com
EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are
observed in real proteins. Currently, the database contains 4867 distinct peptide sequences …
observed in real proteins. Currently, the database contains 4867 distinct peptide sequences …
NIEluter: Predicting peptides eluted from HLA class I molecules
The immune system has evolved to make a diverse repertoire of peptides processed from
self and foreign proteomes, which are displayed in antigen-binding grooves of major …
self and foreign proteomes, which are displayed in antigen-binding grooves of major …
The electrostatic landscape of MHC-peptide binding revealed using inception networks
Predictive modeling of macromolecular recognition and protein-protein complementarity
represents one of the cornerstones of biophysical sciences. However, such models are often …
represents one of the cornerstones of biophysical sciences. However, such models are often …
A review on the methods of peptide-MHC binding prediction
Y Liu, X Ouyang, ZX Xiao, L Zhang… - Current …, 2020 - ingentaconnect.com
Background: T lymphocyte achieves an immune response by recognizing antigen peptides
(also known as T cell epitopes) through major histocompatibility complex (MHC) molecules …
(also known as T cell epitopes) through major histocompatibility complex (MHC) molecules …
BERTMHC: improved MHC–peptide class II interaction prediction with transformer and multiple instance learning
J Cheng, K Bendjama, K Rittner, B Malone - Bioinformatics, 2021 - academic.oup.com
Motivation Increasingly comprehensive characterization of cancer-associated genetic
alterations has paved the way for the development of highly specific therapeutic vaccines …
alterations has paved the way for the development of highly specific therapeutic vaccines …
Building proteomic tool boxes to monitor MHC class I and class II peptides
FR Schumacher, L Delamarre, S Jhunjhunwala… - …, 2017 - Wiley Online Library
Major histocompatibility complex Class I (MHCI) and Class II (MHCII) presented peptides
powerfully modulate T cell immunity and play a vital role in generating effective anti‐tumor …
powerfully modulate T cell immunity and play a vital role in generating effective anti‐tumor …
Strength in numbers: achieving greater accuracy in MHC-I binding prediction by combining the results from multiple prediction tools
Background Peptides derived from endogenous antigens can bind to MHC class I
molecules. Those which bind with high affinity can invoke a CD8+ immune response …
molecules. Those which bind with high affinity can invoke a CD8+ immune response …
MHC2SKpan: a novel kernel based approach for pan-specific MHC class II peptide binding prediction
L Guo, C Luo, S Zhu - BMC genomics, 2013 - Springer
Background Computational methods for the prediction of Major Histocompatibility Complex
(MHC) class II binding peptides play an important role in facilitating the understanding of …
(MHC) class II binding peptides play an important role in facilitating the understanding of …
A tissue-based draft map of the murine MHC class I immunopeptidome
H Schuster, W Shao, T Weiss, PGA Pedrioli, P Roth… - Scientific data, 2018 - nature.com
The large array of peptides presented to CD8+ T cells by major histocompatibility complex
(MHC) class I molecules is referred to as the MHC class I immunopeptidome. Although the …
(MHC) class I molecules is referred to as the MHC class I immunopeptidome. Although the …
High-throughput modeling and scoring of TCR-pMHC complexes to predict cross-reactive peptides
Motivation The binding of T-cell receptors (TCRs) to their target peptide MHC (pMHC)
ligands initializes the cell-mediated immune response. In autoimmune diseases such as …
ligands initializes the cell-mediated immune response. In autoimmune diseases such as …