Quercetin Downregulates Cyclooxygenase‐2 Expression and HIF‐1α/VEGF Signaling‐Related Angiogenesis in a Mouse Model of Abdominal Aortic Aneurysm
L Wang, H Wu, L Xiong, X Liu, N Yang… - BioMed Research …, 2020 - Wiley Online Library
Objective. Abdominal aortic aneurysm (AAA) development has been characterized by
increased expression of vascular endothelial growth factor (VEGF), which contributes to …
increased expression of vascular endothelial growth factor (VEGF), which contributes to …
Quercetin, a flavonoid with anti-inflammatory activity, suppresses the development of abdominal aortic aneurysms in mice
L Wang, B Wang, H Li, H Lu, F Qiu, L Xiong… - European Journal of …, 2012 - Elsevier
Inflammation has been implicated as a contributing factor in the development of abdominal
aortic aneurysms (AAA). Quercetin, a natural flavonoid with anti-inflammatory properties, is …
aortic aneurysms (AAA). Quercetin, a natural flavonoid with anti-inflammatory properties, is …
[HTML][HTML] Preventive effects of quercetin against the onset of atherosclerosis-related acute aortic syndromes in mice
M Kondo, Y Izawa-Ishizawa, M Goda… - International journal of …, 2020 - mdpi.com
Atherosclerosis-related acute aortic syndromes, such as aortic aneurysms or aortic
dissection are life-threatening diseases. Since they develop suddenly and progress rapidly …
dissection are life-threatening diseases. Since they develop suddenly and progress rapidly …
[HTML][HTML] Quercetin reduces oxidative stress and inhibits activation of c‑Jun N‑terminal kinase/activator protein‑1 signaling in an experimental mouse model of …
L Wang, X Cheng, H Li, F Qiu… - Molecular …, 2014 - spandidos-publications.com
Oxidative stress is becoming increasingly linked to the pathogenesis of abdominal aortic
aneurysms (AAAs). The antioxidant activity of flavonoids has attracted attention for their …
aneurysms (AAAs). The antioxidant activity of flavonoids has attracted attention for their …
Inhibitory effects of quercetin on angiogenesis in larval zebrafish and human umbilical vein endothelial cells
Angiogenesis plays an essential role in many physiological and pathological processes.
Quercetin, a plant pigment and traditional Chinese medicinal herb, is an important flavonoid …
Quercetin, a plant pigment and traditional Chinese medicinal herb, is an important flavonoid …
[HTML][HTML] Quercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR-2 regulated AKT/mTOR/P70S6K signaling pathways
P Pratheeshkumar, A Budhraja, YO Son, X Wang… - 2012 - journals.plos.org
Angiogenesis is a crucial step in the growth and metastasis of cancers, since it enables the
growing tumor to receive oxygen and nutrients. Cancer prevention using natural products …
growing tumor to receive oxygen and nutrients. Cancer prevention using natural products …
Quercetin, a dietary-derived flavonoid, possesses antiangiogenic potential
W Tan, L Lin, M Li, YX Zhang, Y Tong, D Xiao… - European Journal of …, 2003 - Elsevier
Quercetin, a dietary-derived flavonoid, suppresses tumor growth in vitro and in vivo, and
inhibits the activity of tyrosine kinase. The effects of quercetin on the angiogenic process …
inhibits the activity of tyrosine kinase. The effects of quercetin on the angiogenic process …
Curcumin attenuates the development of thoracic aortic aneurysm by inhibiting VEGF expression and inflammation
Angiogenesis is an important process in the pathogenesis of aortic aneurysm. The aim of the
present study was to investigate the angiogenic balance and the expression of vascular …
present study was to investigate the angiogenic balance and the expression of vascular …
Acacetin inhibits VEGF expression, tumor angiogenesis and growth through AKT/HIF-1α pathway
LZ Liu, Y Jing, LL Jiang, XE Jiang, Y Jiang… - Biochemical and …, 2011 - Elsevier
Acacetin (5, 7-dihydroxy-4′-methoxyflavone) is a flavone compound, some of which have
anti-cancerous effects. Vascular endothelial growth factor (VEGF) plays an important role in …
anti-cancerous effects. Vascular endothelial growth factor (VEGF) plays an important role in …
Curcumin attenuates angiotensin II‐induced abdominal aortic aneurysm by inhibition of inflammatory response and ERK signaling pathways
QQ Hao, X Chen, XY Wang, B Dong… - Evidence‐Based …, 2014 - Wiley Online Library
Background and Objectives. Curcumin has long been used to treat age‐related diseases,
such as atherosclerosis and coronary heart disease. In this study, we explored the effects of …
such as atherosclerosis and coronary heart disease. In this study, we explored the effects of …