Concentration-dependent differential effects of quercetin on rat aortic smooth muscle cells

CM Shih, H Lin, YC Liang, WS Lee, WF Bi… - European journal of …, 2004 - Elsevier
Quercetin is one of the most ubiquitous bioflavonoids in foods of plant origin. Although
quercetin is generally considered to provide protection against oxidative injury and …

[HTML][HTML] Hesperetin inhibits vascular formation by suppressing of the PI3K/AKT, ERK, and p38 MAPK signaling pathways

GD Kim - Preventive nutrition and food science, 2014 - ncbi.nlm.nih.gov
Hesperetin has been shown to possess a potential anti-angiogenic effect, including vascular
formation by endothelial cells. However, the mechanisms underlying the potential anti …

Quercetin attenuates cell survival, inflammation, and angiogenesis via modulation of AKT signaling in murine T-cell lymphoma

AK Maurya, M Vinayak - Nutrition and cancer, 2017 - Taylor & Francis
ABSTRACT AKT signaling is important to maintaining normal physiology. Hyperactivation of
AKT signaling is frequent in cancer, which maintains a high oxidative state in a tumor …

Acacetin Inhibits In Vitro and In Vivo Angiogenesis and Downregulates Stat Signaling and VEGF Expression

TA Bhat, D Nambiar, D Tailor, A Pal, R Agarwal… - Cancer Prevention …, 2013 - AACR
Angiogenesis is an effective target in cancer control. The antiangiogenic efficacy and
associated mechanisms of acacetin, a plant flavone, are poorly known. In the present study …

[HTML][HTML] Quercetin-4′-O-β-D-glucopyranoside (QODG) Inhibits Angiogenesis by Suppressing VEGFR2-Mediated Signaling in Zebrafish and Endothelial Cells

C Lin, M Wu, J Dong - PloS one, 2012 - journals.plos.org
Background Angiogenesis plays an important role in many physiological and pathological
processes. Identification of small molecules that block angiogenesis and are safe and …

Quercetin glucosides promote ischemia-induced angiogenesis, but do not promote tumor growth

M Sumi, N Tateishi, H Shibata, T Ohki, M Sata - Life sciences, 2013 - Elsevier
Aims Dietary flavonoid intake shows a significant inverse association with mortality from
coronary heart disease, incidence of myocardial infarction and stroke. Quercetin is one of …

Quercetin and its metabolites improve vessel function by inducing eNOS activity via phosphorylation of AMPK

Y Shen, KD Croft, JM Hodgson, R Kyle, ILE Lee… - Biochemical …, 2012 - Elsevier
Quercetin is a major flavonoid in a wide range of fruits and vegetables. Consumption of
quercetin may contribute to a reduction in risk of cardiovascular disease (CVD). Following …

Quercetin inhibits invasion and angiogenesis of esophageal cancer cells

Y Liu, CL Li, QQ Xu, D Cheng, KD Liu… - Pathology-Research and …, 2021 - Elsevier
Background Esophageal carcinoma has poor prognosis and novel therapies for esophageal
carcinoma are urgently needed. Quercetin is a natural flavonoid compound that can be …

Quercetin exerts multiple inhibitory effects on vascular smooth muscle cells: role of ERK1/2, cell-cycle regulation, and matrix metalloproteinase-9

SK Moon, GO Cho, SY Jung, SW Gal, TK Kwon… - Biochemical and …, 2003 - Elsevier
The French paradox has been attributed to the antioxidant properties of flavonoids present
in the red wine. Quercetin, a bioflanoid present in the human diet, is known to inhibit …

Quercetin alleviates hypercholesterolemic diet induced inflammation during progression and regression of atherosclerosis in rabbits

S Bhaskar, KS Kumar, K Krishnan, H Antony - Nutrition, 2013 - Elsevier
OBJECTIVE: Recent advances have established a fundamental role for inflammation in
mediating all stages of atherosclerosis, from initiation through progression. Quercetin may …