Background Hepatocellular carcinoma (HCC) is characterized by late detection and fast
progression, and it is believed that epigenetic disruption may be the cause of its molecular …

Hepatocellular Carcinoma (HCC) is one of the leading causes of cancer-associated
mortality worldwide. However, the role of epigenetic changes such as aberrant DNA …

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is one of the most frequent
human cancers and a major cause of cancer-related death worldwide. The major risk factors …

Epigenetic deregulation has emerged as a driver in human malignancies. There is no clear
understanding of the epigenetic alterations in hepatocellular carcinoma (HCC) and of the …

Aberrant DNA methylation has been implicated in the development of hepatocellular
carcinoma (HCC). Our aim was to clarify its molecular mechanism and to identify useful …

Background Hepatocellular carcinoma (HCC) is one of the most common cancers and
frequently presents with an advanced disease at diagnosis. There is only limited knowledge …

Epigenetic changes as well as genetic changes are mechanisms of tumorigenesis. We
aimed to identify novel genes that are silenced by DNA hypermethylation in hepatocellular …

We aimed to identify the specific subset of tumor suppressor genes (TSGs) that are
methylation‐silenced during the earliest steps of hepatocarcinogenesis, and to further …

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and has a
poor prognosis. Epigenetic modification has been shown to be deregulated during HCC …

Hepatocellular Carcinoma (HCC) is one of the most common cancers in the world and it is
often associated with poor prognosis. Liver transplantation and resection are two currently …