Benzo [a] pyrene decreases global and gene specific DNA methylation during zebrafish development

X Fang, C Thornton, BE Scheffler, KL Willett - Environmental toxicology and …, 2013 - Elsevier
DNA methylation is important for gene regulation and is vulnerable to early-life exposure to
environmental contaminants. We found that direct waterborne benzo [a] pyrene (BaP) …

Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo [a] pyrene exposure

J Corrales, X Fang, C Thornton, W Mei… - … and Physiology Part C …, 2014 - Elsevier
Abstract Benzo [a] pyrene (BaP) is an established carcinogen and reproductive and
developmental toxicant. BaP exposure in humans and animals has been linked to infertility …

Role of DNA methylation in altered gene expression patterns in adult zebrafish (Danio rerio) exposed to 3, 3', 4, 4', 5-pentachlorobiphenyl (PCB 126)

N Aluru, SI Karchner, KS Krick, W Zhu… - Environmental …, 2018 - academic.oup.com
There is growing evidence that environmental toxicants can affect various physiological
processes by altering DNA methylation patterns. However, very little is known about the …

Transcriptomic changes in zebrafish embryos and larvae following benzo [a] pyrene exposure

X Fang, J Corrales, C Thornton, T Clerk… - Toxicological …, 2015 - academic.oup.com
Abstract Benzo [a] pyrene (BaP) is an environmentally relevant carcinogenic and endocrine
disrupting compound that causes immediate, long-term, and multigenerational health …

Global DNA methylation in gonads of adult zebrafish Danio rerio under bisphenol A exposure

Y Liu, Y Zhang, S Tao, Y Guan, T Zhang… - … and environmental safety, 2016 - Elsevier
Altered DNA methylation is pervasively associated with changes in gene expression and
signal transduction after exposure to a wide range of endocrine disrupting chemicals. As a …

Associations between behavioral effects of bisphenol A and DNA methylation in zebrafish embryos

PA Olsvik, P Whatmore, SJ Penglase… - Frontiers in …, 2019 - frontiersin.org
Endocrine-disrupting contaminants have been associated with aberrant changes in
epigenetic pathways in animals. In this study, zebrafish embryos were exposed bisphenol A …

Bisphenol A causes reproductive toxicity, decreases dnmt1 transcription, and reduces global DNA methylation in breeding zebrafish (Danio rerio)

LV Laing, J Viana, EL Dempster, M Trznadel… - Epigenetics, 2016 - Taylor & Francis
Bisphenol A (BPA) is a commercially important high production chemical widely used in
epoxy resins and polycarbonate plastics, and is ubiquitous in the environment. Previous …

Tris (1, 3-dichloro-2-propyl) phosphate induces genome-wide hypomethylation within early zebrafish embryos

DC Volz, JK Leet, A Chen, HM Stapleton… - … science & technology, 2016 - ACS Publications
Tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) is a high-production volume
organophosphate-based plasticizer and flame retardant widely used within the United …

Zebrafish as a model to study the role of DNA methylation in environmental toxicology

JH Kamstra, P Aleström, JM Kooter, J Legler - Environmental Science and …, 2015 - Springer
Environmental epigenetics is a rapidly growing field which studies the effects of
environmental factors such as nutrition, stress, and exposure to compounds on epigenetic …

Zebrafish embryos as a screen for DNA methylation modifications after compound exposure

MC Bouwmeester, S Ruiter, T Lommelaars… - Toxicology and applied …, 2016 - Elsevier
Modified epigenetic programming early in life is proposed to underlie the development of an
adverse adult phenotype, known as the Developmental Origins of Health and Disease …