Investigation of prolonged hypobaric hypoxia-induced change in rat brain using T2 relaxometry and diffusion tensor imaging at 7T

S Koundal, S Gandhi, T Kaur, R Trivedi, S Khushu - Neuroscience, 2015 - Elsevier
The present study examines the change in water diffusion properties of the corpus callosum
(CC) and the hippocampus, in response to prolonged hypobaric hypoxia (HH) stress, using …

Neurometabolic and structural alterations in rat brain due to acute hypobaric hypoxia: in vivo 1H MRS at 7 T

S Koundal, S Gandhi, T Kaur, S Khushu - NMR in Biomedicine, 2014 - Wiley Online Library
In response to hypobaric hypoxia (HH), which occurs at high altitude, the brain undergoes
deleterious changes at the structural and metabolite level. In vivo T2 weighted imaging …

Cell death/proliferation and alterations in glial morphology contribute to changes in diffusivity in the rat hippocampus after hypoxia—ischemia

M Anderova, I Vorisek, H Pivonkova… - Journal of Cerebral …, 2011 - journals.sagepub.com
To understand the structural alterations that underlie early and late changes in hippocampal
diffusivity after hypoxia/ischemia (H/I), the changes in apparent diffusion coefficient of water …

Abnormal brain activity in rats with sustained hypobaric hypoxia exposure: a resting-state functional magnetic resonance imaging study

H Yuan, Y Wang, PF Liu, YL Yue, JS Guo… - Chinese Medical …, 2019 - mednexus.org
Background: Hypobaric hypoxia (HH) exposure at high altitudes can result in a decline in
cognitive function, which may have a serious impact on the daily life of people who migrate …

[HTML][HTML] Exposure to hyperbaric O2 levels leads to blood-brain barrier breakdown in rodents

YM Danino, R Rabinovitz, I Kirshenboim… - Fluids and Barriers of …, 2024 - Springer
Introduction Hyperbaric oxygen has been used as a medical treatment tool in hyperbaric
chambers and is an integral part of professional and combat divers' activity. In extreme …

[HTML][HTML] A multimodal MR imaging study of the effect of hippocampal damage on affective and cognitive functions in a rat model of chronic exposure to a plateau …

D Zhu, B He, M Zhang, Y Wan, R Liu, L Wang… - Neurochemical …, 2022 - Springer
Prolonged exposure to high altitudes above 2500 m above sea level (asl) can cause
cognitive and behavioral dysfunctions. Herein, we sought to investigate the effects of chronic …

A single systemic transient hypotension induces long-term changes in rats' MRI parameters and behavior: relation to aging

K Plaschke, K Frauenknecht, C Sommer… - Neurological …, 2009 - Taylor & Francis
Abstract Objectives and Aim: The aim of this work was to examine whether a single 20-
minute systemic hypotension induces short-and long-term changes in 12-and 18-month-old …

Volumetric quantification of brain swelling after hypobaric hypoxia exposure

IA Mórocz, GP Zientara, H Gudbjartsson, S Muza… - Experimental …, 2001 - Elsevier
We applied a novel MR imaging technique to investigate the effect of acute mountain
sickness on cerebral tissue water. Nine volunteers were exposed to hypobaric hypoxia …

Temporal and spatial changes in glial cells during chronic hypobaric hypoxia: role in neurodegeneration

A Dheer, V Jain, N Kushwah, R Kumar, D Prasad… - Neuroscience, 2018 - Elsevier
Ascend to high altitude results in a drastic change in the environmental conditions an
individual is exposed to. As the altitude increases there is a decrease in partial pressure of …

Diffusion magnetic resonance imaging study of a rat hippocampal slice model for acute brain injury

TM Shepherd, PE Thelwall… - Journal of Cerebral …, 2003 - journals.sagepub.com
Diffusion magnetic resonance imaging (MRI) provides a surrogate marker of acute brain
pathology, yet few studies have resolved the evolution of water diffusion changes during the …