Hearing loss affects hundreds of millions of people worldwide by dampening or cutting off
their auditory connection to the world. Current treatments for sensorineural hearing loss …

Hair cells are sensory cells that transduce motion into neural signals. In the cochlea, they
are used to detect sound waves in the environment and turn them into auditory signals that …

Purpose To provide an overview of the methodologies involved in the field of hair cell
regeneration. First, the author provides a tutorial on the biotechnological foundations of this …

Hearing and balance deficits often affect humans and other mammals permanently, because
their ears stop producing hair cells within a few days after birth. But production occurs …

Damage and loss of hair cells in the inner ear is the most frequent cause of hearing loss
(HL), since mammalian hair cells are not replenished once lost. To date, the treatment of HL …

Cochlear hair cells (HCs) are mechanosensory receptors that transduce sound into
electrical signals. HC damage in nonmammalian vertebrates induces surrounding …

Loss of hair cells (HCs) accounts for most sensorineural hearing loss, and regeneration of
cochlear HCs is considered as the ultimate strategy for restoring hearing. Several lines of …

During their development inner hair cells (IHCs), the primary sensory receptors in the
mammalian cochlea, undergo a meticulously orchestrated series of changes in the …

Noise-induced hearing loss (NIHL) affects a large number of military personnel and civilians.
Regenerating inner-ear cochlear hair cells (HCs) is a promising strategy to restore hearing …

Hair cell regeneration in the avian cochlea was first identified 10 years ago in studies of hair
cell loss following noise damage and aminoglycoside treatment. Since then, numerous …