DNA methylation and chromatin–unraveling the tangled web
KD Robertson - Oncogene, 2002 - nature.com
Methylation of cytosines within the CpG dinucleotide by DNA methyltransferases is involved
in regulating transcription and chromatin structure, controlling the spread of parasitic …
in regulating transcription and chromatin structure, controlling the spread of parasitic …
Structure and function of eukaryotic DNA methyltransferases
T Chen, E Li - Current topics in developmental biology, 2004 - Elsevier
DNA methylation is a common epigenetic modification found in eukaryotic organisms
ranging from fungi to mammals. Over the past 15 years, a number of eukaryotic DNA …
ranging from fungi to mammals. Over the past 15 years, a number of eukaryotic DNA …
DNA methylation: shared and divergent features across eukaryotes
Chemical modification of nucleotide bases in DNA provides one mechanism for conveying
information in addition to the genetic code. 5-methylcytosine (5mC) represents the most …
information in addition to the genetic code. 5-methylcytosine (5mC) represents the most …
New concepts in DNA methylation
A Jeltsch, RZ Jurkowska - Trends in biochemical sciences, 2014 - cell.com
The widely-cited model of maintenance of DNA methylation at CpG sites implies that DNA
methylation is introduced by the Dnmt3 de novo DNA methyltransferases during early …
methylation is introduced by the Dnmt3 de novo DNA methyltransferases during early …
Local chromatin microenvironment determines DNMT activity: from DNA methyltransferase to DNA demethylase or DNA dehydroxymethylase
MGP van der Wijst, M Venkiteswaran, H Chen, GL Xu… - Epigenetics, 2015 - Taylor & Francis
Insights on active DNA demethylation disproved the original assumption that DNA
methylation is a stable epigenetic modification. Interestingly, mammalian DNA …
methylation is a stable epigenetic modification. Interestingly, mammalian DNA …
[引用][C] The essentials of DNA methylation
A Bird - cell, 1992 - Elsevier
An obstacle to progress in understanding eukaryotic DNA methylation has been the lack of a
good genetic systemthe most favorable eukaryotes for genetic analysis (yeasts …
good genetic systemthe most favorable eukaryotes for genetic analysis (yeasts …
In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse
Methylation of cytosines (5meC) is a widespread heritable DNA modification. During
mammalian development, two global demethylation events are followed by waves of de …
mammalian development, two global demethylation events are followed by waves of de …
Active demethylation in mouse zygotes involves cytosine deamination and base excision repair
Background DNA methylation in mammals is an epigenetic mark necessary for normal
embryogenesis. During development active loss of methylation occurs in the male …
embryogenesis. During development active loss of methylation occurs in the male …
DNA methylation: past, present and future directions
KD Robertson, P A. Jones - Carcinogenesis, 2000 - academic.oup.com
DNA methylation, or the covalent addition of a methyl group to cytosine within the context of
the CpG dinucleotide, has profound effects on the mammalian genome. These effects …
the CpG dinucleotide, has profound effects on the mammalian genome. These effects …
DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases
CC Chen, KY Wang, CKJ Shen - Journal of Biological Chemistry, 2013 - ASBMB
Methylation at the 5-position of DNA cytosine on the vertebrate genomes is accomplished by
the combined catalytic actions of three DNA methyltransferases (DNMTs), the de novo …
the combined catalytic actions of three DNA methyltransferases (DNMTs), the de novo …