2788 sequences is dynamic and can be altered by histone-modifying enzymes and by the
exchange of histone variants. The recently identified inverse relationship between the …

Both DNA methylation and histone modification are involved in establishing patterns of gene
repression during development. Certain forms of histone methylation cause local formation …

Methylation of DNA at position five of the cytosine ring occurs at most CpG dinucleotides in
the mammalian genome and is essential for embryonic viability. With several of the key …

The field of epigenetics has recently moved to the forefront of studies relating to diverse
processes such as transcriptional regulation, chromatin structure, genome integrity, and …

DNA methylation plays a central role in the epigenetic regulation of gene expression during
development and disease. Remarkably, the complex and changing patterns of genomic …

Cytosine methylation is a com-mon DNA modification found in most eukaryotic organisms
including plants, animals, and fungi (1, 2). The addition of a methyl group to cytosine …

DNA methylation is a crucial epigenetic modification of the genome that is involved in
regulating many cellular processes. These include embryonic development, transcription …

DNA methylation is a major epigenetic modification of vertebrate genomes that is mostly
associated with transcriptional repression. During embryogenesis, DNA methylation …

DNA methylation is an epigenetic modification which plays an important role in chromatin
organization and gene expression. DNA methylation can silence genes and repetitive …

Changes in cellular phenotypes and identities are fundamentally regulated by epigenetic
mechanisms including DNA methylation, post-translational histone modifications and …