The methylome: approaches for global DNA methylation profiling
S Beck, VK Rakyan - Trends in Genetics, 2008 - cell.com
DNA methylation plays a critical role in genome function both in health and disease. Almost
60 years after the discovery of 5-methyl cytosine and∼ 25 years since the discovery that …
60 years after the discovery of 5-methyl cytosine and∼ 25 years since the discovery that …
Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes
DNA methylation is one of the most important heritable epigenetic modifications of the
genome and is involved in the regulation of many cellular processes. Aberrant DNA …
genome and is involved in the regulation of many cellular processes. Aberrant DNA …
Deciphering the epigenetic code: an overview of DNA methylation analysis methods
Significance: Methylation of cytosine in DNA is linked with gene regulation, and this has
profound implications in development, normal biology, and disease conditions in many …
profound implications in development, normal biology, and disease conditions in many …
[HTML][HTML] DNA methylation: a timeline of methods and applications
A Harrison, A Parle-McDermott - Frontiers in genetics, 2011 - frontiersin.org
DNA methylation is a biochemical process where a DNA base, usually cytosine, is
enzymatically methylated at the 5-carbon position. An epigenetic modification associated …
enzymatically methylated at the 5-carbon position. An epigenetic modification associated …
[HTML][HTML] Profiling genome-wide DNA methylation
DNA methylation is an epigenetic modification that plays an important role in regulating
gene expression and therefore a broad range of biological processes and diseases. DNA …
gene expression and therefore a broad range of biological processes and diseases. DNA …
Genome-scale DNA methylation analysis
SD Fouse, RP Nagarajan, JF Costello - Epigenomics, 2010 - Taylor & Francis
The haploid human genome contains approximately 29 million CpGs that exist in a
methylated, hydroxymethylated or unmethylated state, collectively referred to as the DNA …
methylated, hydroxymethylated or unmethylated state, collectively referred to as the DNA …
DNA methylation methods: Global DNA methylation and methylomic analyses
S Li, TO Tollefsbol - Methods, 2021 - Elsevier
DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …
significant involvement for numerous biological processes in health and disease. The …
Profiling DNA methylomes from microarray to genome-scale sequencing
YW Huang, THM Huang… - Technology in cancer …, 2010 - journals.sagepub.com
DNA cytosine methylation is a central epigenetic modification which plays critical roles in
cellular processes including genome regulation, development and disease. Here, we review …
cellular processes including genome regulation, development and disease. Here, we review …
Genome‐wide DNA methylation profiling
M Bibikova, JB Fan - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …
access the methylation status for a large number of genes or the entire genome should …
Principles and challenges of genome-wide DNA methylation analysis
PW Laird - Nature Reviews Genetics, 2010 - nature.com
Methylation of cytosine bases in DNA provides a layer of epigenetic control in many
eukaryotes that has important implications for normal biology and disease. Therefore …
eukaryotes that has important implications for normal biology and disease. Therefore …
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