DNA methylation is a major epigenetic modification in the genomes of higher eukaryotes. In
vertebrates, DNA methylation occurs predominantly on the CpG dinucleotide, and …

The molecular pathways that regulate gain and loss of DNA methylation during mammalian
development need to be tightly balanced to maintain a physiological equilibrium. Here we …

In this review, we will provide a brief reminder of epigenetic phenomena in general, and
DNA methylation in particular. We will then underline the characteristics of the in vivo …

DNA methylation is an epigenetic mark that is erased in the early embryo and then re-
established at the time of implantation. In this Review, dynamics of DNA methylation during …

DNA-methylation patterns are important for regulating genome functions, and are
determined by the enzymatic processes of methylation and demethylation. The …

DNA methylation plays a role in the repression of gene expression in animal cells. In the
mouse preimplantation embryo, most genes are unmethylated but a wave of de novo …

DNA methylation is a heritable epigenetic modification of cytosine residues within CpG
dinucleotides associated with the modulation of gene expression and found at 20–30 million …

Epigenetic modifications of DNA such as methylation are important for genome function
during development and in adults. DNA methylation has central importance for genomic …

DNA methylation represents a form of genome annotation that mediates gene repression by
serving as a maintainable mark that can be used to reconstruct silent chromatin following …

A large number of studies have documented the methylation patterns of individual genes
and repeated sequences in different tissues of various mammalian species. This has …